Picture of blood cells

Open Access research which pushes advances in bionanotechnology

Strathprints makes available scholarly Open Access content by researchers in the Strathclyde Institute of Pharmacy & Biomedical Sciences (SIPBS) , based within the Faculty of Science.

SIPBS is a major research centre in Scotland focusing on 'new medicines', 'better medicines' and 'better use of medicines'. This includes the exploration of nanoparticles and nanomedicines within the wider research agenda of bionanotechnology, in which the tools of nanotechnology are applied to solve biological problems. At SIPBS multidisciplinary approaches are also pursued to improve bioscience understanding of novel therapeutic targets with the aim of developing therapeutic interventions and the investigation, development and manufacture of drug substances and products.

Explore the Open Access research of SIPBS. Or explore all of Strathclyde's Open Access research...

Strathprints

Droplet formation in microfluidic cross-junctions

Liu, Haihu and Zhang, Yonghao (2011) Droplet formation in microfluidic cross-junctions. Physics of Fluids, 23 (8). ISSN 1070-6631

[img] PDF
Zhang_YH_Droplet_formation_in_microfluidic_cross_junctions_Sept_2011.pdf
Final Published Version
Download (1MB)
    [img]
    Preview
    		 PDF
    Zhang_YH_strathprints_Droplet_formation_in_a_T_shaped_microfluidic_junction_Aug_09.pdf
    Preprint
    Download (613kB)| Preview

      Abstract

      Using a lattice Boltzmann multiphase model, three-dimensional numerical simulations have been performed to understand droplet formation in microfluidic cross-junctions at low capillary numbers. Flow regimes, consequence of interaction between two immiscible fluids, are found to be dependent on the capillary number and flow rates of the continuous and dispersed phases. A regime map is created to describe the transition from droplets formation at a cross-junction (DCJ), downstream of cross-junction to stable parallel flows. The influence of flow rate ratio, capillary number, and channel geometry is then systematically studied in the squeezing-pressure-dominated DCJ regime. The plug length is found to exhibit a linear dependence on the flow rate ratio and obey power-law behavior on the capillary number. The channel geometry plays an important role in droplet breakup process. A scaling model is proposed to predict the plug length in the DCJ regime with the fitting constants depending on the geometrical parameters.

      Author(s):Liu, Haihu and Zhang, Yonghao ORCID: https://orcid.org/0000-0002-0683-7050
      Item type:Article
      ID code:32838
      Keywords:microfluidics, lattice Boltzmann model, droplet formation, flow regime, cross-junctions, Mechanical engineering and machinery, Physics, Mechanical Engineering, Fluid Flow and Transfer Processes
      Subjects:Technology > Mechanical engineering and machinery
      Science > Physics
      Department:Faculty of Engineering > Mechanical and Aerospace Engineering
      Technology and Innovation Centre > Advanced Engineering and Manufacturing
      Depositing user: Pure Administrator
      Date deposited:29 Aug 2011 10:39
      Last modified:26 Jun 2019 00:13
      Related URLs:
      URI:https://strathprints.strath.ac.uk/id/eprint/32838
      Export data:
      CORE (COnnecting REpositories)