S-acylation by the DHHC protein family

Greaves, Jennifer and Chamberlain, Luke H (2010) S-acylation by the DHHC protein family. Biochemical Society Transactions, 38 (2). pp. 522-524.

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Abstract

A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.