Medicines from nature : are natural products still relevant to drug discovery?
Harvey, A L (1999) Medicines from nature : are natural products still relevant to drug discovery? Trends in Pharmacological Sciences, 20 (5). pp. 196-198. ISSN 0165-6147
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Historically, most drugs have been derived from natural products, but there has been a shift away from their use with the increasing predominance of molecular approaches to drug discovery. Nevertheless, their structural diversity makes them a valuable source of novel lead compounds against newly discovered therapeutic targets. Technical advances in analytical techniques mean that the use of natural products is easier than before. However, there is a widening gap between natural-product researchers in countries rich in biodiversity and drug discovery scientists immersed in proteomics and high-throughput screening.
| Author(s): | Harvey, A L | Item type: | Article |
|---|---|
| ID code: | 31617 |
| Keywords: | biological products, pharmaceutical chemistry, molecular cloning, preclinical drug evaluation, ecosystem, humans, Pharmacy and materia medica, Toxicology, Pharmacology |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Depositing user: | Pure Administrator |
| Date deposited: | 13 Jul 2011 08:56 |
| Last modified: | 20 Sep 2019 02:36 |
| URI: | https://strathprints.strath.ac.uk/id/eprint/31617 |
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