Medicines from nature : are natural products still relevant to drug discovery?

Harvey, A L (1999) Medicines from nature : are natural products still relevant to drug discovery? Trends in Pharmacological Sciences, 20 (5). pp. 196-198. ISSN 0165-6147 (https://doi.org/10.1016/S0165-6147(99)01346-2)

Abstract

Historically, most drugs have been derived from natural products, but there has been a shift away from their use with the increasing predominance of molecular approaches to drug discovery. Nevertheless, their structural diversity makes them a valuable source of novel lead compounds against newly discovered therapeutic targets. Technical advances in analytical techniques mean that the use of natural products is easier than before. However, there is a widening gap between natural-product researchers in countries rich in biodiversity and drug discovery scientists immersed in proteomics and high-throughput screening.

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  Item type:	Article
  ID code:	31617
  Dates:	Date Event 1 May 1999 Published
  Keywords:	biological products, pharmaceutical chemistry, molecular cloning, preclinical drug evaluation, ecosystem, humans, Pharmacy and materia medica, Toxicology, Pharmacology
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	13 Jul 2011 08:56
  Last modified:	03 Jun 2023 02:08
  URI:	https://strathprints.strath.ac.uk/id/eprint/31617