Formation of artificial lipid bilayers using droplet dielectrophoresis
Aghdaei, Sara and Sandison, M.E. and Zagnoni, Michele and Green, Nicolas G. and Morgan, Hywel (2008) Formation of artificial lipid bilayers using droplet dielectrophoresis. Lab on a Chip, 8 (10). 1617–1620. ISSN 1473-0197 (https://doi.org/10.1039/b807374k)
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We describe the formation of artificial bilayer lipid membranes (BLMs) by the controlled, electrical manipulation of aqueous droplets immersed in a lipid–alkane solution. Droplet movement was generated using dielectrophoresis on planar microelectrodes covered in a thin insulator. Droplets, surrounded by lipid monolayers, were brought into contact and spontaneously formed a BLM. The method produced BLMs suitable for single-channel recording of membrane protein activity and the technique can be extended to create programmable BLM arrays and networks.
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Item type: Article ID code: 29052 Dates: DateEventOctober 2008Published13 August 2008Published OnlineSubjects: Technology > Engineering (General). Civil engineering (General) > Bioengineering Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Faculty of Engineering > Biomedical Engineering
Faculty of Engineering > Electronic and Electrical EngineeringDepositing user: Pure Administrator Date deposited: 28 Mar 2011 09:20 Last modified: 09 Aug 2024 19:40 URI: https://strathprints.strath.ac.uk/id/eprint/29052