The solid state

Florence, A.J.; Florence, Alexander and Siepmann, Juergen, eds. (2009) The solid state. In: Modern pharmaceutics, Fifth Edition. Informa Healthcare, New York, USA. ISBN 9781420065657

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Abstract

Many active pharmaceutical ingredients (APIs) can exist in more than one solid-state form, including crystalline polymorphs, solvates, salts, cocrystals, and noncrystalline or amorphous solids (Fig. 1; Table 1). Hence, assessment and control of the solid-state structure of APIs is necessary to ensure efficient and reproducible processing, manufacturing, and storage; to satisfy regulatory authorities; to protect intellectual property; and ultimately to deliver safe, effective, and high-quality medicinal products. This section introduces key practical aspects of solid-state pharmaceuticals, with a specific emphasis on crystalline solids and their preparation, handling, and analysis, particularly in the context of preclinical drug development and pharmaceutical manufacture.

ORCID iDs

Florence, A.J. ORCID logoORCID: https://orcid.org/0000-0002-9706-8364; Florence, Alexander and Siepmann, Juergen
  • Item type:Book Section
    ID code:26060
    Dates:
    Date
    Event
    May 2009
    Published
    Keywords:solid state, drug delivery, excipients, tablets, aerosols, techniques, pharmaceuticals, drug absorption, pharmacokinetics, dose forms, preformulation, optimization, systems, release, bioequivalence, processes, products, pharmaceutics, personalized medicines, evaluation, physics, in vivo imaging, biotechnology, Pharmacy and materia medica
    Subjects:Medicine > Pharmacy and materia medica
    Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Depositing user: Strathprints Administrator
    Date deposited:28 Sep 2010 13:54
    Last modified:25 Aug 2021 00:45
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/26060
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