Metal-free reductive cleavage of N-O bonds in Weinreb amides by an organic neutral super-electron donor
Cutulic, S.P.Y. and Murphy, J.A. and Farwaha, H. and Zhou, S.Z. and Chrystal, E. (2008) Metal-free reductive cleavage of N-O bonds in Weinreb amides by an organic neutral super-electron donor. Synlett (14). pp. 2132-2136. ISSN 0936-5214 (http://dx.doi.org/10.1055/s-2008-1078240)
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The scope of neutral organic super-electron donors as reducing agents has been extended to include the reductive cleavage of N-O bonds in Weinreb amides. This methodology proved to be applicable to a large array of substrates to afford their reduced counterparts in good to excellent yields. The variation in reactivity within the set of tested amides is rationalised.
ORCID iDs
Cutulic, S.P.Y., Murphy, J.A., Farwaha, H. ORCID: https://orcid.org/0000-0003-0570-005X, Zhou, S.Z. and Chrystal, E.;-
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Item type: Article ID code: 19489 Dates: DateEvent22 August 2008PublishedSubjects: Science > Chemistry Department: Faculty of Science > Pure and Applied Chemistry Depositing user: Strathprints Administrator Date deposited: 08 Jun 2010 09:24 Last modified: 11 Nov 2024 04:03 URI: https://strathprints.strath.ac.uk/id/eprint/19489
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