Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa

Ibrahim, S.R.M. and Edrada-Ebel, R.A. and Mohamed, G.A. and Youssef, D.T.A. and Wray, V. and Proksch, P. (2008) Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa. ARKIVOC - Online Journal of Organic Chemistry. pp. 164-171. ISSN 1551-7004

Abstract

From the ethyl acetate fraction of the Indonesian sponge Callyspongia aerizusa extract, a new cyclic peptide named callyaerin G was isolated. Its structure was elucidated by extensive 1D and 2D NMR (1H NMR, TOCSY and ROESY) studies and mass spectrometric data (ESI- and FAB-MS). The stereochemistry was determined by Marfey's analysis. Callyaerin G was found to exhibit cytotoxic activity when tested against different cancer cell lines.

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• Item metadata

  Item type:	Article
  ID code:	19450
  Dates:	Date Event 16 April 2008 Published
  Keywords:	callyspongia aerizusa, callyaerin G, marfey's analysis, cytotoxicity, Pharmacy and materia medica, Organic Chemistry, SDG 3 - Good Health and Well-being, SDG 14 - Life Below Water
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Strathprints Administrator
  Date deposited:	26 May 2010 10:17
  Last modified:	15 Sep 2021 16:29
  Related URLs:	Journal or Publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/19450