Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa
Ibrahim, S.R.M. and Edrada-Ebel, R.A. and Mohamed, G.A. and Youssef, D.T.A. and Wray, V. and Proksch, P. (2008) Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa. ARKIVOC - Online Journal of Organic Chemistry. pp. 164-171. ISSN 1551-7004
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From the ethyl acetate fraction of the Indonesian sponge Callyspongia aerizusa extract, a new cyclic peptide named callyaerin G was isolated. Its structure was elucidated by extensive 1D and 2D NMR (1H NMR, TOCSY and ROESY) studies and mass spectrometric data (ESI- and FAB-MS). The stereochemistry was determined by Marfey's analysis. Callyaerin G was found to exhibit cytotoxic activity when tested against different cancer cell lines.
| Author(s): | Ibrahim, S.R.M., Edrada-Ebel, R.A., Mohamed, G.A., Youssef, D.T.A., Wray, V. and Proksch, P. | Item type: | Article |
|---|---|
| ID code: | 19450 |
| Keywords: | callyspongia aerizusa, callyaerin G, marfey's analysis, cytotoxicity, Pharmacy and materia medica, Organic Chemistry |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Depositing user: | Strathprints Administrator |
| Date deposited: | 26 May 2010 10:17 |
| Last modified: | 23 Aug 2019 09:09 |
| Related URLs: | |
| URI: | https://strathprints.strath.ac.uk/id/eprint/19450 |
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