Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa

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Ibrahim, S.R.M. and Edrada-Ebel, R.A. and Mohamed, G.A. and Youssef, D.T.A. and Wray, V. and Proksch, P. (2008) Callyaerin g, a new cytotoxic cyclic peptide from the marine sponge callyspongia aerizusa. ARKIVOC - Online Journal of Organic Chemistry. pp. 164-171. ISSN 1551-7004

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Abstract

From the ethyl acetate fraction of the Indonesian sponge Callyspongia aerizusa extract, a new cyclic peptide named callyaerin G was isolated. Its structure was elucidated by extensive 1D and 2D NMR (1H NMR, TOCSY and ROESY) studies and mass spectrometric data (ESI- and FAB-MS). The stereochemistry was determined by Marfey's analysis. Callyaerin G was found to exhibit cytotoxic activity when tested against different cancer cell lines.

ORCID iDs

Ibrahim, S.R.M., Edrada-Ebel, R.A. ORCID logoORCID: https://orcid.org/0000-0003-2420-1117, Mohamed, G.A., Youssef, D.T.A., Wray, V. and Proksch, P.;
CORE (COnnecting REpositories)