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Strathprints makes available Open Access scholarly outputs exploring both the technical aspects of computer security, but also the regulation of existing or emerging technologies. A research specialism of the Department of Computer & Information Sciences (CIS) is computer security. Researchers explore issues surrounding web intrusion detection techniques, malware characteristics, textual steganography and trusted systems. Digital forensics and cyber crime are also a focus.

Meanwhile, the School of Law and its Centre for Internet Law & Policy undertake studies on Internet governance. An important component of this work is consideration of privacy and data protection questions and the increasing focus on cybercrime and 'cyberterrorism'.

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A new tetrahydrofuran derivative from the endophytic fungus chaetomium sp isolated from otanthus maritimus

Aly, A.H. and Debbab, A. and Edrada-Ebel, R.A. and Wray, V. and Muller, W.E.G. and Lin, W.H. and Ebel, R. and Proksch, P., BMBF (Funder), MOST (Funder) (2009) A new tetrahydrofuran derivative from the endophytic fungus chaetomium sp isolated from otanthus maritimus. Zeitschrift fur Naturforschung C, 64 (5-6). pp. 350-354. ISSN 0939-5075

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Abstract

A hitherto unidentified endophytic strain of the genus Chaetomium, isolated from the medicinal plant Otanthus maritimus, yielded a new tetrahydrofuran derivative, aureonitolic acid (1), along with 5 known natural products, 2-6. The structure of 1 was determined by extensive spectroscopic analysis and comparison with reported data. Extracts of the fungus, grown either in liquid culture or on solid rice media, exhibited considerable cytotoxic activity when tested in vitro against L5178Y mouse lymphoma cells. Compounds 2 and 6 showed significant growth inhibition against L5178Y cells with EC50, values of 7.0 and 2.7 mu g/mL, respectively, whereas 1 was inactive.