Determining biomolecular structures by time-resolved fluorescence
Rolinski, O.J. and Hernandez-Santana, A. and Graham, D. (2006) Determining biomolecular structures by time-resolved fluorescence. Proceedings of SPIE - The International Society for Optical Engineering, 6047 (60472N). (http://dx.doi.org/10.1117/12.710984)
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This article demonstrates a new fluorescence resonance energy transfer (FRET) based approach to determine the donor-acceptor distributions and apply it to two model molecular systems: double stranded DNA labeled with Hoechst 33258 and FAM, and perylene randomly surrounded by cobalt ions in a bulk solution. The approach makes some generic assumptions regarding the FRET kinetics, but no a priori assumptions regarding the distribution function.
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Item type: Article ID code: 18173 Dates: DateEvent2006PublishedNotes: Fourth International Conference on Photonics and Imaging in Biology and Medicine. Subseries of Proceedings of SPIE - International Society for Optical Engineering. Vol. 6047, Part 2. Progress in Biomedical Optics and Imaging, Vol. 7(2) Subseries of Proceedings of SPIE. Subjects: Science > Physics > Optics. Light Department: Faculty of Science > Physics
Faculty of Science > Pure and Applied ChemistryDepositing user: Strathprints Administrator Date deposited: 14 Apr 2010 14:53 Last modified: 08 Apr 2024 17:29 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/18173
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