Picture of UK Houses of Parliament

Leading national thinking on politics, government & public policy through Open Access research

Strathprints makes available scholarly Open Access content by researchers in the School of Government & Public Policy, based within the Faculty of Humanities & Social Sciences.

Research here is 1st in Scotland for research intensity and spans a wide range of domains. The Department of Politics demonstrates expertise in understanding parties, elections and public opinion, with additional emphases on political economy, institutions and international relations. This international angle is reflected in the European Policies Research Centre (EPRC) which conducts comparative research on public policy. Meanwhile, the Centre for Energy Policy provides independent expertise on energy, working across multidisciplinary groups to shape policy for a low carbon economy.

Explore the Open Access research of the School of Government & Public Policy. Or explore all of Strathclyde's Open Access research...

Influence of the beta-agonist salbutamol on claw horn lesions and walking soundness in finishing pigs

Penny, R.H.C. and Guise, H.J. and Rolph, T.P. and Tait, J.A. and Johnston, A.M. and Kempson, S.A. and Gettinby, G. (1994) Influence of the beta-agonist salbutamol on claw horn lesions and walking soundness in finishing pigs. Veterinary Record, 135 (16). pp. 374-381. ISSN 0042-4900

Full text not available in this repository.Request a copy from the Strathclyde author

Abstract

The effects of feeding the beta-adrenergic agonist salbutamol to pigs at levels between 0.5 and 5.0 mg/kg feed for different periods were studied in six experiments. The feet and ability to walk of pigs weighing 30 to 100 kg were examined at intervals. False sand-crack, white-line and heel erosion lesions were classified as mild or severe, and corns and wall haemorrhages were also recorded. At each examination the pig was given a grade for the overall severity of its foot lesions. Salbutamol fed at 1.0 to 5.0 mg/kg feed, for as little as 21 to 28 days, increased the frequency (P < 0.05 to 0.001) and often the severity (P < 0.05) of the foot lesions, the higher doses tending to produce more severe lesions, and the overall foot grades deteriorated (P < 0.001). The effects on both sexes were similar. No changes were observed when 0.5 mg/kg was fed for 56 days. Despite the severity of many of the foot lesions, the pigs became lame in only one experiment. Electron microscopy indicated that salbutamol was interfering with horn production, but light microscopy revealed no changes in skin sections. These findings suggested that salbutamol was not directly affecting the function of keratinocytes. Supplementing the diet of the pigs with biotin and methionine did not delay, or prevent, the effects of salbutamol.