Sequence-specific dna detection using high-affinity lna-functionalized gold nanoparticles

McKenzie, Fiona and Faulds, K. and Graham, D. (2007) Sequence-specific dna detection using high-affinity lna-functionalized gold nanoparticles. Small, 3 (11). pp. 1866-1868. ISSN 1613-6810 (http://dx.doi.org/10.1002/smll.200700225)

Abstract

The functionalization of gold nanoparticles with locked nucleic acid (LNA; see image) is reported. These nanoconjugate probes offer immense stability and selectivity towards complementary DNA, allowing the detection of specific DNA sequences.

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• Item metadata

  Item type:	Article
  ID code:	17130
  Dates:	Date Event November 2007 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Strathprints Administrator
  Date deposited:	17 Apr 2010 14:59
  Last modified:	21 Aug 2024 12:38
  URI:	https://strathprints.strath.ac.uk/id/eprint/17130