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Open Access research with a European policy impact...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the European Policies Research Centre (EPRC).

EPRC is a leading institute in Europe for comparative research on public policy, with a particular focus on regional development policies. Spanning 30 European countries, EPRC research programmes have a strong emphasis on applied research and knowledge exchange, including the provision of policy advice to EU institutions and national and sub-national government authorities throughout Europe.

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Development of a cell population migration assay

Whitton, A. and Black, R.A. and Flint, D.J. (2009) Development of a cell population migration assay. European Cells and Materials, 18 (Suppl.). p. 110. ISSN 1473-2262

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Abstract

Cellular migration is central to many physiological and pathological processes, from wound healing and the immune response to cancer cell invasion. Many in-vitro assays have been developed to study these processes and can be classified by the nature of the assay, for example migration of single cells or entire populations, as well as migration on a planar surface or through a 3D structure. This work concerns the development of an assay to study the migration of whole populations of cells across a deformable planar substratum, which may be coated in adsorbed adhesion molecules. The technique detailed below was developed from the Teflon fence assay.