Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata

Wang, Yao and Edrada-Ebel, RuAngelie and Tsevegsurent, Nanzad and Sendker, Jandirk and Braun, Manfred and Wray, Victor and Lin, Wenhan and Proksch, Peter (2009) Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata. Journal of Natural Products, 72 (4). pp. 671-675. ISSN 0163-3864 (http://dx.doi.org/10.1021/np800782f)

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Abstract

Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A−E (1−5). The structures were unambiguously elucidated on the basis of one- and two-dimensional NMR (1H, 13C, COSY, HMBC, HMQC, and ROESY) and mass spectrometric data. Compounds 1−5 exhibited antioxidative activity when analyzed in the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 and 5 the antioxidant activities were stronger than that of the well-known naturally occurring stilbene antioxidant resveratrol.

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