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Number of items: 8.

Article

Lim, Keng Gat and Gray, A and Anthony, Nahoum Guillaume Hsuan and MacKay, Simon and Pyne, Susan and Pyne, Nigel (2014) Resveratrol and its oligomers : modulation of sphingolipid metabolism and signaling in disease. Archives of Toxicology. ISSN 0340-5761 (In Press)

Lim, Keng Gat and Tonelli, Francesca Romana and Berdyshev, Evgeny and Gorshkova, Irina and Leclercq, Tamara and Pitson, Stuart M and Bittman, Robert and Pyne, Susan and Pyne, Nigel (2012) Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells : functional differences between sphingosine kinase 1a and 1b. International Journal of Biochemistry and Cell Biology, 44 (9). pp. 1457-1464. ISSN 1357-2725

Lim, Keng Gat and Gray, Alexander I and Pyne, Susan and Pyne, Nigel J (2012) Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival. British Journal of Pharmacology, 166 (5). pp. 1605-1616.

Pyne, Nigel J and Tonelli, Francesca and Lim, Keng Gat and Long, Jaclyn and Edwards, Joanne and Pyne, Susan (2012) Targeting sphingosine kinase 1 in cancer. Advances in Biological Regulation, 52 (1). 31–38. ISSN 2212-4934

Pyne, N. J. and Tonelli, F. and Lim, K. G. and Long, J. S. and Edwards, J. and Pyne, S. (2012) Sphingosine 1 phosphate signalling in cancer. Biochemical Society Transactions, 40 (1). pp. 94-100. ISSN 0300-5127

Lim, Keng Gat and Sun, Chaode and Bittman, Robert and Pyne, Nigel J and Pyne, Susan (2011) (R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor : Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells. Cellular Signalling, 23 (10). pp. 1590-1595.

Lim, Keng and Tonelli, Francesca Romana and Li, Z. and Lu, X. and Bittman, R. and Pyne, Susan and Pyne, Nigel (2011) FTY720 analogues as sphingosine kinase 1 inhibitors : enzyme inhibition kinetics, allosterism, proteasomal degradation and actin rearrangement in MCF-7 breast cancer cells. Journal of Biological Chemistry, 286 (21). pp. 18633-18640. ISSN 0021-9258

Loveridge, Carolyn and Tonelli, Francesca and Leclercq, Tamara and Lim, Keng Gat and Long, Jaclyn S and Berdyshev, Evgeny and Tate, Rothwelle J and Natarajan, Viswanathan and Pitson, Stuart M and Pyne, Nigel J and Pyne, Susan (2010) The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells. Journal of Biological Chemistry, 285 (50). pp. 38841-38852. ISSN 1083-351X

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