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Research under the microscope...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Number of items: 7.

Article

Lim, Keng Gat and Tonelli, Francesca Romana and Berdyshev, Evgeny and Gorshkova, Irina and Leclercq, Tamara and Pitson, Stuart M and Bittman, Robert and Pyne, Susan and Pyne, Nigel (2012) Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells : functional differences between sphingosine kinase 1a and 1b. International Journal of Biochemistry and Cell Biology, 44 (9). pp. 1457-1464. ISSN 1357-2725

Lim, Keng Gat and Gray, Alexander I and Pyne, Susan and Pyne, Nigel J (2012) Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival. British Journal of Pharmacology, 166 (5). pp. 1605-1616.

Pyne, Nigel J and Tonelli, Francesca and Lim, Keng Gat and Long, Jaclyn and Edwards, Joanne and Pyne, Susan (2012) Targeting sphingosine kinase 1 in cancer. Advances in Biological Regulation, 52 (1). 31–38. ISSN 2212-4934

Pyne, N. J. and Tonelli, F. and Lim, K. G. and Long, J. S. and Edwards, J. and Pyne, S. (2012) Sphingosine 1 phosphate signalling in cancer. Biochemical Society Transactions, 40 (1). pp. 94-100. ISSN 0300-5127

Lim, Keng Gat and Sun, Chaode and Bittman, Robert and Pyne, Nigel J and Pyne, Susan (2011) (R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor : Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells. Cellular Signalling, 23 (10). pp. 1590-1595.

Lim, Keng and Tonelli, Francesca Romana and Li, Z. and Lu, X. and Bittman, R. and Pyne, Susan and Pyne, Nigel (2011) FTY720 analogues as sphingosine kinase 1 inhibitors : enzyme inhibition kinetics, allosterism, proteasomal degradation and actin rearrangement in MCF-7 breast cancer cells. Journal of Biological Chemistry, 286 (21). pp. 18633-18640. ISSN 0021-9258

Loveridge, Carolyn and Tonelli, Francesca and Leclercq, Tamara and Lim, Keng Gat and Long, Jaclyn S and Berdyshev, Evgeny and Tate, Rothwelle J and Natarajan, Viswanathan and Pitson, Stuart M and Pyne, Nigel J and Pyne, Susan (2010) The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells. Journal of Biological Chemistry, 285 (50). pp. 38841-38852.

This list was generated on Wed Aug 24 19:28:36 2016 BST.