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Number of items: 26.

Article

Watson, David G and Tonelli, Francesca and Al Osaimi, Manal and Williamson, Leon and Chan, Edmond and Gorshkova, Irina and Berdyshev, Evgeny and Bittman, Robert and Pyne, Nigel J and Pyne, Susan (2013) The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells. Cellular Signalling, 25 (4). pp. 1011-1017.

Tonelli, F. and Alossaimi, M. and Williamson, L. and Tate, R.J. and Watson, D.G. and Chan, E. and Bittman, R. and Pyne, N.J. and Pyne, S. (2013) The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism. British Journal of Pharmacology, 168 (6). pp. 1497-1505.

McAlpine, Fiona and Williamson, Leon E and Tooze, Sharon A and Chan, Edmond Y W (2013) Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2. Autophagy, 9 (3). 361 - 373.

Mleczak, Andrzej and Millar, Sarah and Tooze, Sharon A and Olson, Michael F and Chan, Edmond Y W (2013) Regulation of autophagosome formation by Rho kinase. Cellular Signalling, 25 (1). pp. 1-11. ISSN 0898-6568

Gallagher, Laura E and Chan, Edmond Y W (2013) Early signalling events of autophagy. Essays in biochemistry, 55. pp. 1-15. ISSN 1744-1358

Chan, Edmond Y (2012) Regulation and function of uncoordinated-51 like kinase proteins. Antioxidants and Redox Signaling, 17 (5). pp. 775-785. ISSN 1557-7716

Klionsky, Daniel J. and Abdalla, Fabio C. and Abeliovich, Hagai and Abraham, Robert T. and Acevedo-Arozena, Abraham and Adeli, Khosrow and Agnello, Maria and Al-Zeer, Munir A. and Chan, Edmond and Coombs, Graham and Menzies, Fiona Mary and Mottram, Jeremy (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 8 (4). pp. 445-544. ISSN 1554-8627

Chan, Edmond Y (2009) mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex. Science signaling, 2 (84). pe51. ISSN 1937-9145

Chan, Edmond Y. and Tooze, Sharon A. (2009) Evolution of Atg1 function and regulation. Autophagy, 5 (6). pp. 758-765. ISSN 1554-8627

Razi, M. and Chan, Edmond Y. and Tooze, Sharon A. (2009) Early endosomes and endosomal coatomer are required for autophagy. Journal of Cell Biology, 185 (2). pp. 305-321. ISSN 0021-9525

Chan, Edmond Y. and Longatti, Andrea and McKnight, Nicole C. and Tooze, Sharon A. (2009) Kinase-inactivated ULK proteins inhibit autophagy via their conserved c-terminal domains using an Atg13-independent mechanism. Molecular and Cellular Biology, 29 (1). pp. 157-171. ISSN 0270-7306

Chan, Edmond Y W and Kir, Serkan and Tooze, Sharon A (2007) siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy. Journal of Biological Chemistry, 282 (35). pp. 25464-25474. ISSN 0021-9258

Young, Andrew R.J. and Chan, Edmond Y W and Hu, Xiao Wen and Köchl, Robert and Crawshaw, Samuel G and High, Stephen and Hailey, Dale W and Lippincott-Schwartz, Jennifer and Tooze, Sharon A. (2006) Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. Journal of Cell Science, 119 (18). pp. 3888-3900. ISSN 0021-9533

Köchl, Robert and Hu, Xiao Wen and Chan, Edmond Y W and Tooze, Sharon A (2006) Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic, 7 (2). pp. 129-145. ISSN 1398-9219

Warby, Simon C and Chan, Edmond Y and Metzler, Martina and Gan, Lu and Singaraja, Roshni R and Crocker, Susan F and Robertson, Harold A and Hayden, Michael R (2005) Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo. Human Molecular Genetics, 14 (11). pp. 1569-1577. ISSN 0964-6906

Tang, Tie-Shan and Tu, Huiping and Orban, Paul C and Chan, Edmond Y W and Hayden, Michael R and Bezprozvanny, Ilya (2004) HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca2+ release in primary culture of striatal medium spiny neurons. European Journal of Neuroscience, 20 (7). 1779–1787. ISSN 0953-816X

Tang, Tie-Shan and Tu, Huiping and Chan, Edmond Y W and Maximov, Anton and Wang, Zhengnan and Wellington, Cheryl L and Hayden, Michael R and Bezprozvanny, Ilya (2003) Huntingtin and Huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Neuron, 39 (2). pp. 227-239. ISSN 0896-6273

Chan, E Y W (2002) HIP1 as a marker of aggressive prostate cancer. Clinical genetics, 62 (5). pp. 372-375. ISSN 0009-9163

Luthi-Carter, Ruth and Hanson, Sarah A and Strand, Andrew D and Bergstrom, Donald A and Chun, Wanjoo and Peters, Nikki L and Woods, Annette M and Chan, Edmond Y and Kooperberg, Charles and Krainc, Dimitri and Young, Anne B and Tapscott, Stephen J and Olson, James M (2002) Dysregulation of gene expression in the R6/2 model of polyglutamine disease : parallel changes in muscle and brain. Human Molecular Genetics, 11 (17). pp. 1911-1926. ISSN 0964-6906

Chan, Edmond Y W and Luthi-Carter, Ruth and Strand, Andrew and Solano, Steven M and Hanson, Sarah A and DeJohn, Molly M and Kooperberg, Charles and Chase, Kathryn O and DiFiglia, Marian and Young, Anne B and Leavitt, Blair R and Cha, Jang-Ho J and Aronin, Neil and Hayden, Michael R and Olson, James M (2002) Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Human Molecular Genetics, 11 (17). pp. 1939-1951. ISSN 0964-6906

Chan, Edmond Y W and Nasir, Jamal and Gutekunst, Claire-Anne and Coleman, Sarah and Maclean, Alan and Maas, Alex and Metzler, Martina and Gertsenstein, Marina and Ross, Christopher A and Nagy, Andràs and Hayden, Michael R (2002) Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. Human Molecular Genetics, 11 (8). pp. 945-959. ISSN 0964-6906

Chan, Edmond Y W and Stang, Stacey L and Bottorff, Drell A and Stone, James C (2002) Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity. Molecular carcinogenesis, 33 (4). pp. 189-97. ISSN 0899-1987

Chan, E Y and Stang, S L and Bottorff, D A and Stone, J C (1999) Hypothermic stress leads to activation of Ras-Erk signaling. Journal of Clinical Investigation, 103 (9). pp. 1337-44. ISSN 0021-9738

Hanna, A N and Chan, E Y and Xu, J and Stone, J C and Brindley, D N (1999) A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase. Journal of Biological Chemistry, 274 (18). pp. 12722-9. ISSN 0021-9258

Ebinu, J O and Bottorff, D A and Chan, E Y and Stang, S L and Dunn, R J and Stone, J C (1998) RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs. Science, 280 (5366). pp. 1082-1086. ISSN 0036-8075

Rusiñol, A E and Chan, E Y and Vance, J E (1993) Movement of apolipoprotein B into the lumen of microsomes from hepatocytes is disrupted in membranes enriched in phosphatidylmonomethylethanolamine. Journal of Biological Chemistry, 268 (33). pp. 25168-75. ISSN 0021-9258

This list was generated on Thu Oct 23 11:08:23 2014 BST.