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McConnell, Gail and Trägårdh, Johanna and Amor, Rumelo and Dempster, John and Reid, Es and Amos, William Bradshaw (2016) A novel optical microscope for imaging large embryos and tissue volumes with sub-cellular resolution throughout. eLife. ISSN 2050-084X (In Press)
Sandison, Mairi E. and Dempster, John and McCarron, John G. (2016) The transition of smooth muscle cells from a contractile to a migratory, phagocytic phenotype : direct demonstration of phenotypic modulation. Journal of Physiology. ISSN 1469-7793
Mawlood, Shakhawan K. and Dennany, Lynn and Watson, Nigel and Dempster, John and Pickard, Benjamin S. (2016) Quantification of global mitochondrial DNA methylation levels and inverse correlation with age at two CpG sites. Aging, 8 (4). pp. 636-641. ISSN 1945-4589
Amor, Rumelo and McDonald, Alison and Trägårdh, Johanna and Robb, Gillian and Wilson, Louise and Abdul Rahman, Nor Zaihana and Dempster, John and Amos, William Bradshaw and Bushell, Trevor J. and McConnell, Gail (2016) Widefield two-photon excitation without scanning : live cell microscopy with high time resolution and low photo-bleaching. PLOS One, 11 (1). ISSN 1932-6203
Pinnell, R C and Dempster, J and Pratt, J (2015) Miniature wireless recording and stimulation system for rodent behavioural testing. Journal of Neural Engineering, 12 (6). ISSN 1741-2552
Trägårdh, J. and Robb, G. and Amor, R. and Amos, W. B. and Dempster, J. and McConnell, G. (2015) Exploration of the two-photon excitation spectrum of fluorescent dyes at wavelengths below the range of the Ti:Sapphire laser. Journal of Microscopy. ISSN 0022-2720
Amos, William and Trägårdh, Johanna and Amor, Rumelo and Dempster, John and McConnell, Gail (2014) A new giant lens for confocal mesoscopy. In: Photon14, 2014-09-01 - 2014-09-04, Imperial College London.
Sandison, Mairi and Chalmers, Susan and Dempster, John and McCarron, John (2014) Direct visualisation of smooth muscle cell phenotypic plasticity and migration by long-term imaging. FASEB Journal, 28 (Suppl ). ISSN 0892-6638
Trägårdh, Johanna and Robb, Gillian and Amor, Rumelo and Dempster, John and McConnell, Gail (2014) Efficient excitation of blue emitting dyes by two-photon microscopy at visible wavelengths. In: Focus on Microscopy, FOM 2014, 2014-04-13 - 2014-04-16.
Amos, William and Trägårdh, Johanna and Amor, Rumelo and Dempster, John and McConnell, Gail (2014) A new giant lens for confocal mesoscopy. In: Focus on Microscopy, FOM 2014, 2014-04-13 - 2014-04-16.
Cookson, Emma A and Conte, Ianina L and Dempster, John and Hannah, Matthew J and Carter, Tom (2013) Characterisation of Weibel-Palade body fusion by amperometry in endothelial cells reveals fusion pore dynamics and the effect of cholesterol on exocytosis. Journal of Cell Science, 126 (Pt 23). pp. 5490-5499. ISSN 0021-9533
Norris, G and Amor, R and Dempster, J and Amos, W B and McConnell, G (2012) Increased signals from short-wavelength-excited fluorescent molecules using sub-Ti:Sapphire wavelengths. Journal of Microscopy, 248 (2). pp. 200-207. ISSN 0022-2720
Workman, A.J. and Marshall, G.E. and Rankin, A.C. and Smith, G.L. and Dempster, J. (2012) Transient outward K+ current (ITO) reduction prolongs action potentials and promotes afterdepolarisations : a dynamic-clamp study in human and rabbit cardiac atrial myocytes. Journal of Physiology, 590 (17). 4289–4305.
Amor, R and Norris, G and Dempster, J and Amos, W B and McConnell, G (2012) A compact instrument for adjusting laser beams to be accurately coincident and coaxial and its use in biomedical imaging using wave-mixed laser sources. Review of Scientific Instruments, 83 (8). ISSN 0034-6748
Norris, Greg and Amor, Rumelo and Dempster, John and Amos, William B and McConnell, Gail (2012) A promising new wavelength region for three-photon fluorescence microscopy of live cells. Journal of Microscopy, 246 (3). pp. 266-273.
McDonald, Alison and Harris, John and MacMillan, Debbi and Dempster, John and McConnell, Gail (2012) Light-induced Ca(2+) transients observed in widefield epi-fluorescence microscopy of excitable cells. Biomedical Optics Express, 3 (6). pp. 1266-1273.
Marshall, Gillian E and Russell, Julie A and Tellez, James O and Jhund, Pardeep S and Currie, Susan and Dempster, John and Boyett, Mark R and Kane, Kathleen A and Rankin, Andrew C and Workman, Antony J (2012) Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade. Pflugers Archiv - European Journal of Physiology, 463 (4). pp. 537-548. ISSN 0031-6768
Kueh, S L L and Dempster, John and Head, S I and Morley, J W (2011) Reduced postsynaptic GABAA receptor number and enhanced gaboxadol induced change in holding currents in Purkinje cells of the dystrophin-deficient mdx mouse. Neurobiology of Disease, 43 (3). pp. 558-564.
Knipe, Laura and Meli, Athinoula and Hewlett, Lindsay and Bierings, Ruben and Dempster, John and Skehel, Paul and Hannah, Matthew J and Carter, Tom (2010) A revised model for the secretion of tPA and cytokines from cultured endothelial cells. Blood, 116 (12). pp. 2183-2191. ISSN 0006-4971
MacQuaide, N. and Dempster, J. and Smith, G.L. (2009) Assessment of Sarcoplasmic Reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular Cardiomyocytes. Biophysical Journal, 96 (7). pp. 2744-2754. ISSN 0006-3495
Zinselmeyer, Bernd H. and Dempster, J. and Wokosin, D.L. and Cannon, J. and Pless, Robert and Parker, Ian and Miller, Mark J. (2009) Chapter 16 two-photon microscopy and multidimensional analysis of cell dynamics. Methods in Enzmology, 461. pp. 349-378. ISSN 0076-6879
Gelman, Andrew E. and Li, Wenjun and Richardson, Steven B. and Zinselmeyer, Bernd H. and Lai, Jiaming and Okazaki, Mikio and Kornfeld, Christopher G. and Kreisel, Friederike H. and Sugimoto, Seiichiro and Tietjens, Jeremy R. and Dempster, J. and Patterson, G. Alexander and Krupnick, Alexander S. and Miller, Mark J. and Kreisel, Daniel (2009) Cutting edge: acute lung allograft rejection is independent of secondary lymphoid organs. Journal of Immunology, 182. pp. 3969-3973. ISSN 0022-1767
Babich, Victor and Knipe, Laura and Hewlett, Lindsay and Meli, Athinoula and Dempster, J. and Hannah, Matthew J. and Carter, Tom (2009) Differential effect of extracellular acidosis on the release and dispersal of soluble and membrane proteins secreted from the weibel-palade body. Journal of Biological Chemistry, 284 (18). pp. 12459-12468. ISSN 0021-9258
Babich, Victor and Meli, Athinoula and Knipe, Laura and Dempster, John E. and Skehel, Paul and Hannah, Matthew J. and Carter, Tom (2008) Selective release of molecules from weibel-palade bodies during a lingering kiss. Blood, 111 (11). pp. 5282-5290. ISSN 0006-4971
Farkas, A. and Dempster, J. and Coker, S.J. (2008) Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model. British Journal of Pharmacology, 154 (5). pp. 958-970. ISSN 0007-1188
Mitchell, E.A. and Gentet, L.J. and Dempster, J. and Belelli, D. (2007) GABAA and glycine receptor mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. Journal of Physiology, 583 (3). pp. 1021-1040. ISSN 0022-3751
MacQuaide, N. and Dempster, J. and Smith, G.L. (2007) Measurement and modelling of Ca2+ waves in isolated rabbit ventricular cardiomyocytes. Biophysical Journal, 93 (7). pp. 2581-2595. ISSN 0006-3495
Kane, K.A. and Michael, G. and Dempster, J. and Coker, S.J. (2007) Potentiation of E-4031-induced torsade de pointes by HMR1556 or ATX-II is not predicted by action potential short-term variability or triangulation. British Journal of Pharmacology, 152 (8). pp. 1215-1227. ISSN 0007-1188
Zinselmeyer, B.H. and Dempster, J. and Gurney, A.M. and Wokosin, D.L. and Miller, M. and Ho, H. and Millington, O.R. and Smith, K.M. and Rush, C.M. and Parker, I. and Cahalan, M. and Brewer, J.M. and Garside, P. (2005) In situ characterisation of CD4+ t cell behaviour in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. Journal of Experimental Medicine, 201 (11). pp. 1815-1823. ISSN 0022-1007
MacQuaide, N and Dempster, J and Smith, G (2004) The effect of cytosolic Ca on spontaneous Ca wave characteristics in permeabilised cardiomyocytes from the rabbit. Biophysical Journal, 86 (1 (sup). 111A-112A. ISSN 0006-3495
Zhang, H. and Noble, D. and Cannell, M. and Orchard, C.H. and Lancaster, M. and Jones, S.A. and Boyett, M.R. and Holden, A.V. and Dempster, J. (2003) Dynamics of cardiac intracellular ca2+ handling: from experiments to virtual cells. International Journal of Bifurcation and Chaos, 13 (12). pp. 3535-3560. ISSN 0218-1274
Dempster, J and Wokosin, D L and McCloskey, K D and Girkin, J M and Gurney, A M (2002) WinFluor : an integrated system for the simultaneous recording of cell fluorescence images and electrophysiological signals on a single computer system. British Journal of Pharmacology, 137 (procee). 146P-146P. ISSN 0007-1188
Dempster, J and Graham, J and Sinclair, J and Smith, G L and Thomas, M V (2002) Demonstration of integrator unit and data acquisition software for laser-scanning microscopy. Journal of Physiology, 543 (Supple). 66P-66P. ISSN 0022-3751
Dempster, J. (2001) The laboratory computer : a practical guide for physiologists and neuroscientists. Biological Techniques Series . Academic Press. ISBN 9780122095511
Wolk, R and Sneddon, K P and Dempster, J and Kane, K A and Cobbe, S M and Hicks, M N (2000) Regional electrophysiological effects of left ventricular hypertrophy in isolated rabbit hearts under normal and ischaemic conditions. Cardiovascular Research, 48 (1). pp. 120-128. ISSN 0008-6363
Mair, I D and Lambert, J J and Yang, J and Dempster, J and Peters, J A (1998) Pharmacological characterization of a rat 5-hydroxytryptamine type3 receptor subunit (r5-HT3A(b)) expressed in Xenopus laevis oocytes. British Journal of Pharmacology, 124 (8). pp. 1667-74. ISSN 0007-1188
Tian, L and Prior, C and Dempster, J and Marshall, I G (1997) Hexamethonium- and methyllycaconitine-induced changes in acetylcholine release from rat motor nerve terminals. British Journal of Pharmacology, 122 (6). pp. 1025-1034. ISSN 0007-1188
Dempster, J (1997) A new version of the Strathclyde Electrophysiology software package running within the Microsoft Windows environment. Journal of Physiology, 504 (Suppl.). P57-P57. ISSN 0022-3751
Dempster, John and Prior, Christopher (1995) The use of computer simulations to accompany the laboratory teaching of pharmacological principles. British Journal of Pharmacology, 116 (Suppl). P460-P460. ISSN 0007-1188
Prior, C and Tian, L and Dempster, J and Marshall, I G (1995) Prejunctional actions of muscle relaxants : synaptic vesicles and transmitter mobilization as sites of action. General pharmacology, 26 (4). pp. 659-666. ISSN 0306-3623
Tian, L and Prior, C and Dempster, J and Marshall, I G (1994) Nicotinic antagonist-produced frequency-dependent changes in acetylcholine release from rat motor nerve terminals. Journal of Physiology, 476 (3). pp. 517-529. ISSN 0022-3751
Prior, C and Dempster, J and Marshall, I G (1993) Electrophysiological analysis of transmission at the skeletal neuromuscular junction. Journal of Pharmacological and Toxicological Methods, 30 (1). pp. 1-17. ISSN 1056-8719
Dempster, John (1993) Computer analysis of electrophysiological signals (biological techniques series). Biological techniques series . Academic Press. ISBN 0122089405
Somasundaram, B. and Hoyland, J. and Dempster, John and Riley, J. and Mason, W.T. (1992) Simultaneous patch-clamp and photometric fluorescence ratio measurements of optical probes for ions using a computer-based data acquisition system, PhoCal. Journal of Physiology, 446 (Suppl.). P63-P63. ISSN 0022-3751
Prior, C and Fiekers, J F and Henderson, F and Dempster, J and Marshall, I G and Parsons, R L (1990) End-plate ion channel block produced by lincosamide antibiotics and their chemical analogs. Journal of Pharmacology and Experimental Therapeutics, 255 (3). pp. 1170-1176. ISSN 0022-3565
Lambert, J J and Peters, J A and Hales, T G and Dempster, J (1989) The properties of 5-HT3 receptors in clonal cell lines studied by patch-clamp techniques. British Journal of Pharmacology, 97 (1). pp. 27-40. ISSN 0007-1188
Estrella, D and Green, K L and Prior, C and Dempster, J and Halliwell, R F and Jacobs, R S and Parsons, S M and Parsons, R L and Marshall, I G (1988) A further study of the neuromuscular effects of vesamicol (AH5183) and of its enantiomer specificity. British Journal of Pharmacology, 93 (4). pp. 759-768. ISSN 0007-1188
Dempster, John (1987) A range of computer programs for electrophysiological signal analysis using the IBM PC AT. Journal of Physiology, 392 (Suppl.). P20-P20. ISSN 0022-3751
Dempster, J and Jones, S V and Marshall, I G (1987) A kinetic analysis of the endplate ion channel blocking action of disopyramide and its optical isomers. British Journal of Pharmacology, 90 (2). pp. 299-307. ISSN 0007-1188
Dempster, John (1986) The use of the driving function in the analysis of endplate current kinetics. Journal of Neuroscience Methods, 18 (3). pp. 277-285. ISSN 0165-0270
DeCoursey, T E and Dempster, J and Hutter, O F (1984) Inward rectifier current noise in frog skeletal muscle. Journal of Physiology, 349 (1). pp. 299-327. ISSN 0022-3751
DeCoursey, T.E. and Dempster, John and Hutter, O.F. (1982) A non-linear mathematical model representing the consequence of voltage decrement in the transverse tubular system on the measured conductance-voltage curve for the inward rectifier in frog skeletal muscle. Journal of Physiology, 329 (Suppl.). P7-P8. ISSN 0022-3751