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Number of items: 37.

Article

Salvia, Marie-Virginie and Addison, Fiona and Alniss, Hasan Y H and Buurma, Niklaas J and Khalaf, Abedawn and MacKay, Simon and Anthony, Nahoum G and Suckling, Colin and Evstigneev, Maxim P and Santiago, Adrian Hernandez and Waigh, Roger and Parkinson, John (2013) Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove. Biophysical Chemistry, 179. pp. 1-11. ISSN 0301-4622

Alniss, Hasan Y and Anthony, Nahoum Guillaume Husan and Khalaf, Abedawn and Mackay, Simon and Suckling, Colin and Waigh, Roger and Wheate, Nial and Parkinson, John (2012) Rationalising sequence selection by ligand assemblies in the DNA minor groove : the case for thiazotropsin A. Chemical Science, 3 (3). pp. 711-722. ISSN 2041-6520

Kasim, L.S. and Ferro, Valerie and Odukoya, OA and Ukpo, GE and Seidel, Veronique and Gray, Alexander and Waigh, Roger (2011) Cytotoxicity of isolated compounds from the extracts of Struchium sparganophora (Linn) Ktze asteraceae. Pakistan journal of pharmaceutical sciences, 24 (4). pp. 475-478. ISSN 1011-601X

Kasim, L.S. and Ferro, V.A. and Odkoya, O.A. and Ukpo, G.E. and Seidel, Veronique and Gray, A.I. and Waigh, Roger (2011) Evaluation of cytotoxic and antimicrobial activities of Struchium sparganophora (Linn) Ktze Asteraceae. Journal of Medicinal Plant Research, 5 (6). pp. 862-867. ISSN 1996-0875

Elegami, A.A. and Gray, A.I. and Waigh, R.D. and Khalid, H.E. (2009) Bioactive constituents from bergia suffruticosa. Planta Medica, 75 (9). p. 963. ISSN 0032-0943

Coxon, Geoffrey D. and Furman, Brian L. and Harvey, Alan L. and McTavish, John and Mooney, Mark H. and Arastoo, Mahmoud and Kennedy, A.R. and Tettey, J.N.A. and Waigh, R.D. (2009) Benzylguanidines and other galegine analogues inducing weight loss in mice. Journal of Medicinal Chemistry, 52 (11). pp. 3457-3463. ISSN 0022-2623

Parkinson, J.A. and Khalaf, A.I. and Anthony, N.G. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2009) Comparison of DNA complex formation behaviour for two closely related lexitropsin analogues. Helvetica Chimica Acta, 92 (5). pp. 795-822. ISSN 0018-019X

Mooney, M.H. and Fogarty, S. and Stevenson, C. and Gallagher, A.M. and Palit, P. and Hawley, S.A. and Hardie, D.G. and Coxon, Geoffrey and Waigh, Roger and Tate, R. and Harvey, Alan and Furman, Brian (2008) Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice. British Journal of Pharmacology, 153 (8). pp. 1669-1677. ISSN 0007-1188

Anthony, Nahoum Guillaume Hsuan and Breen, D. and Clarke, Joanna and Donoghue, Gavin and Drummond, Allan J. and Ellis, Elizabeth and Gemmell, Curtis G. and Helesbeux, Jean-Jacques and Hunter, Iain. S. and Khalaf, Abedawn and MacKay, Simon and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2007) Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry, 50 (24). pp. 6116-6125. ISSN 0022-2623

Araya, F.G. and Huchet, G. and McGroarty, I. and Skellern, G.G. and Waigh, R.D. (2007) Capillary electrophoresis for studying drug-DNA interactions. Methods, 42 (2). pp. 141-149. ISSN 1046-2023

Kennedy, Alan and Khalaf, Abedawn I. and Suckling, Colin J. and Waigh, Roger D. (2006) 3-Nitro-1-(triisopropylsilyl)-1H-pyrrole. Acta Crystallographica Section E: Structure Reports, 62 (8). o3282-o3284. ISSN 1600-5368

Suckling, C.J. and Hampshire, Andrew J. and Khairallah, Hannah and Khalaf, A.I. and Ebrahimabadi, Abdolrasoul H. and Waigh, R.D. and Brown, Tom and Fox, Keith R. (2006) DNA sequence recognition by an imidazole-containing isopropyl thiazole polyamide (thiazotropsin b). Bioorganic and Medicinal Chemistry Letters, 16 (13). pp. 3469-3474.

Anthony, N.G. and Huchet, G. and Johnston, B.F. and Parkinson, B.F. and Suckling, C.J. and Waigh, R.D. and Mackay, S.P. (2005) In Silico Footprinting of Ligands Binding to the Minor Groove of DNA. Journal of Chemical Information and Modeling, 45 (6). pp. 1896-1907. ISSN 1549-9596

Alvarez, R.G. and Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. (2005) 2-(1-Piperidinyl)-1,3-benzothiazole. Acta Crystallographica Section E: Structure Reports, 61. pp. 569-570. ISSN 1600-5368

Al-Hiari, Yusuf M. and Bennett, Stephen J. and Cox, Brian and Davies, Robert J. and Khalaf, Abedawn I. and Waigh, Roger D. and Worsley, Alan J. (2005) Steps towards a practical synthesis of macrocyclic bisbenzylisoquinolines. Journal of Heterocyclic Chemistry, 42 (4). pp. 647-659. ISSN 0022-152X

Khalaf, A.I. and Ebrahimabadi, A.H. and Drummond, A.J. and Anthony, N.G. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2004) Synthesis and antimicrobial activity of some netropsin analogues. Organic and Biomolecular Chemistry, 2 (21). pp. 3119-3127. ISSN 1477-0520

Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. (2004) Methyl 2-amino-5-iso­propyl-1,3-thia­zole-4-carboxyl­ate. Acta Crystallographica Section E: Structure Reports, 60 (9). pp. 1510-1512. ISSN 1600-5368

Anthony, N.G. and Johnston, B.F. and Khalaf, A.I. and Mackay, S.P. and Parkinson, J.A. and Suckling, C.J. and Waigh, R.D. (2004) Short Lexitropsin that Recognizes the DNA Minor Groove at 5'-ACTAGT-3': Understanding the Role of Isopropyl-thiazole. Journal of the American Chemical Society, 126 (36). pp. 11338-11349. ISSN 0002-7863

Anthony, N.G. and Johnston, B.F. and Mackay, S.P. and Suckling, C.J. and Waigh, R.D. (2004) An in silico footprinting technique to study ligand interactions in the minor groove of DNA. Drugs of the Future, 29 (Suppl. A). p. 150. ISSN 0377-8282

Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. (2004) Ethyl 2-amino-4-isopropyl-1,3-thiazole-5-carboxylate. Acta Crystallographica Section E: Structure Reports, 60 (8). pp. 1188-1190. ISSN 1600-5368

James, P.L. and Merkina, E.E. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. and Brown, T. and Fox, K.R. (2004) DNA sequence recognition by an isopropyl substituted thiazole polyamide. Nucleic Acids Research, 32 (11). pp. 3410-3417. ISSN 0305-1048

Anthony, N.G. and Fox, K.R. and Johnston, B.F. and Khalaf, A.I. and Mackay, S.P. and McGroarty, I.S. and Parkinson, J.A. and Skellern, G.G. and Suckling, C.J. and Waigh, R.D. (2004) DNA binding of a short lexitropsin. Bioorganic and Medicinal Chemistry Letters, 14 (5). pp. 1353-1356. ISSN 0960-894X

Khalaf, A.I. and Waigh, R.D. and Drummond, A.J. and Pringle, B. and McGroarty, I. and Skellern, G.G. and Suckling, C.J. (2004) Distamycin Analogues with Enhanced Lipophilicity: Synthesis and Antimicrobial Activity. Journal of Medicinal Chemistry, 47 (8). pp. 2133-2156. ISSN 0022-2623

Katerere, D.R. and Gray, A.I. and Kennedy, A.R. and Nash, R.J. and Waigh, R.D. (2004) Cyclobutanes from Combretum albopunctatum. Phytochemistry, 65 (4). pp. 433-438. ISSN 0031-9422

Kennedy, A.R. and Khalaf, A.I. and Suckling, C.J. and Waigh, R.D. (2003) Ethyl 5-oxo-2,5-dihydro-4-isoxazolecarboxylate hydroxylamine salt. Acta Crystallographica Section E: Structure Reports, 59 (9). pp. 1410-1412. ISSN 1600-5368

Katerere, D.R. and Gray, A. and Nash, R.J. and Waigh, R.D. (2003) Antimicrobial activity of pentacyclic triterpenes isolated from African combretaceae. Phytochemistry, 63 (1). pp. 81-99. ISSN 0031-9422

Elegami, A.A. and Bates, C.D. and Gray, A. and Mackay, S.P. and Skellern, G.G. and Waigh, R.D. (2003) Two very unusual macrocyclic flavonoids from the water lily nymphaea lotus. Phytochemistry, 63 (6). pp. 727-731. ISSN 0031-9422

Kennedy, Alan and Khalaf, Abedawn and Suckling, Colin and Waigh, Roger (2001) Ethyl 2-aminooxazole-5-carboxylate. Acta Crystallographica Section E: Structure Reports, 57. o832-o833. ISSN 1600-5368

Khalaf, A.I. and Alvarez, R.G. and Suckling, C.J. and Waigh, R.D. (2000) Unexpected Dealkylation During Nucleophilic Substitution: Synthesis of 2-N,N-Dialkylamino Benzoxazoles and Benzothiazoles. Tetrahedron, 56 (43). pp. 8567-8571. ISSN 0040-4020

Khalaf, A.I. and Pitt, A.R. and Scobie, M. and Suckling, C.J. and Urwin, J. and Waigh, R.D. and Young, S.C. and Fishleigh, R.V. and Fox, K.R. (2000) DNA Binding, Solubility, and Partitioning Characteristics of Extended Lexitropsins. Journal of Medicinal Chemistry, 43 (17). pp. 3257-3266. ISSN 0022-2623

Khalaf, A.I. and Pitt, A.R. and Scobie, M. and Suckling, C.J. and Urwin, J. and Waigh, R.D. and Young, S.C. and Fishleigh, R.V. and Wylie, W.A. (2000) The Synthesis of Some Head to Head Linked DNA Minor Groove Binders. International Journal of Chemical Research, 56 (29). pp. 5225-5239. ISSN 0975-3699

Khalaf, A.I. and Pitt, A.R. and Scobie, M. and Suckling, C.J. and Urwin, J. and Waigh, R.D. and Young, S.C. and Fishleigh, R.V. (2000) The synthesis of some indole-containing amino acids as linkers for the construction of DNA minor groove binders. International Journal of Chemical Research, 2000 (6). pp. 264-265. ISSN 0975-3699

Khalaf, Abedawn I. and Pitt, Andrew R. and Scobie, Martin and Suckling, Colin J. and Urwin, John and Waigh, Roger D. and Fishleigh, Robert V. and Young, Stephen C. (2000) Synthesis of novel DNA binding agents: indole-containing analogs of bis-netropsin. International Journal of Chemical Research (6). pp. 264-265. ISSN 0975-3699

Kennedy, Alan and Khalaf, Abedawn I. and Pitt, Andrew P. and Scobie, Martin and Suckling, Colin J. and Urwin, John and Waigh, Roger D. and Young, Stephen C. (1999) Methyl 2-amino-4-(methoxymethyl)thiazole-5-carboxylate. Acta Crystallographica Section C: Crystal Structure Communications, C55 (7). ii, IUC9900072. ISSN 0108-2701

Book Section

Suckling, C.J. and Waigh, R.D. and Khalaf, A.L. and Parkinson, J. and Hunter, I.S. (2003) Minor groove binders substituted by lipophilic groups. In: 19th International Congress on Heterocyclic Chemistry. Elsevier, p. 98. ISBN 0-080443-04-4

Patent

Khalaf, Abedawn (2008) Novel hydrophobic minor groove binders. .

Khalaf, Abedawn (2003) DNA Minor Groove Binders. .

This list was generated on Thu Dec 25 04:09:01 2014 GMT.