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Article

Gibriel, Abdullah and Tate, Rothwelle and Yu, Yongbin and Rawson-Lax, E. and Hammer, HM and Tettey, Justice Nii Addy and Pyne, Nigel and Converse, Carolyn (2013) The p.Arg86Gln change in GARP2 (glutamic acid-rich protein-2) is a common West African-related polymorphism. Gene, 515 (1). pp. 155-158. ISSN 03781119

Patkar, Shalmali Satish and Tate, Rothwelle and Modo, M. and Plevin, Robin and Carswell, Hilary (2012) Conditionally immortalised neural stem cells promote functional recovery and brain plasticity after transient focal cerebral ischaemia in mice. Stem Cell Research, 8 (1). 14–25.

Lemarié, Fanny and Croft, Daniel and Tate, Rothwelle and Ryan, Kevin M. and Dufès, Christine (2012) Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system. Biomaterials, 33. pp. 2701-2709. ISSN 0142-9612

Tonelli, Francesca and Al Osaimi, Manal and Williamson, Leon and Tate, Rothwelle J and Watson, David G and Chan, Edmond and Bittman, Robert and Pyne, Nigel J and Pyne, Susan (2012) The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism. British Journal of Pharmacology.

Aldawsari, Hibah Mobarak and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Tetley, Laurence and Dufès, Christine (2011) Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex. Biomaterials, 32 (25). pp. 5889-5899. ISSN 0142-9612

Aldawsari, Hibah Mobarak and Sundara Raj, Behin and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Tetley, Laurence and Dufès, Christine (2011) Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex. Nanomedicine: Nanotechnology, Biology and Medicine, 7 (5). pp. 815-823.

Loveridge, Carolyn and Tonelli, Francesca and Leclercq, Tamara and Lim, Keng Gat and Long, Jaclyn S and Berdyshev, Evgeny and Tate, Rothwelle J and Natarajan, Viswanathan and Pitson, Stuart M and Pyne, Nigel J and Pyne, Susan (2010) The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells. Journal of Biological Chemistry, 285 (50). pp. 38841-38852. ISSN 1083-351X

Koppu, Swati and Oh, Yew Jinn and Edrada-Ebel, R. and Blatchford, David R. and Tetley, L. and Tate, R. and Dufès, Christine (2010) Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA. Journal of Controlled Release, 143 (2). pp. 215-221. ISSN 0168-3659

Aldawsari, Hibah Mobarak and Sundara Raj, Behin and Edrada-Ebel, Ruangelie and Blatchford, David and Tate, Rothwelle and Dufès, Christine (2010) Enhanced transfection efficacy of polyethylenimine by surface modification with arginine, lysine, and leucine. Controlled Release Society Newsletter, 27 (6). pp. 12-14.

Patkar, S. and Tate, R. and Modo, M. and Plevin, R.J. and Carswell, H.V.O. (2009) Characterisation of neural stem cells for oestrogen in vitro: potential for improving stem cell based therapy for stroke. Journal of Cerebral Blood Flow and Metabolism, 29. S554-S555.

Wheate, N.J. and Abbott, Grainne M. and Tate, Rothwelle J. and Clements, Caorl J. and Edrada-Ebel, RuAngelie and Johnston, B.F. (2009) Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2μ-dpzm]2+ and its implications for anticancer drug delivery. Journal of Inorganic Biochemistry, 103 (3). pp. 448-454. ISSN 0162-0134

Mooney, M.H. and Fogarty, S. and Stevenson, C. and Gallagher, A.M. and Palit, P. and Hawley, S.A. and Hardie, D.G. and Coxon, Geoffrey and Waigh, Roger and Tate, R. and Harvey, Alan and Furman, Brian (2008) Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice. British Journal of Pharmacology, 153 (8). pp. 1669-1677. ISSN 0007-1188

Gopal, P. and Tate, R. and Pow, E. and Hill, D. and Connolly, J.G. (2007) The role of the amino acid residue at α1:189 in the binding of neuromuscular blocking agents to mouse and human muscle nicotinic acetylcholine receptors. British Journal of Pharmacology, 150 (7). pp. 920-931. ISSN 0007-1188

Egan, C.A. and Houston, K.M. and Alcocer, M.J.C. and Solovyova, A. and Tate, R. and Lochnit, G. and McInnes, I.B. and Harnett, M.M. (2006) Lack of immunological cross-reactivity between parasite-derived and recombinant forms of es-62, a secreted protein of acanthocheilonema viteae. Parasitology, 132 (2). pp. 263-274. ISSN 0031-1820

Frame, Mhairi J and Tate, Rothwelle and Adams, David R and Morgan, Keith M and Houslay, M D and Vandenabeele, Peter and Pyne, Nigel J (2003) Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1). European Journal of Biochemistry, 270 (5). pp. 962-970. ISSN 0014-2956

Gurney, A.M. and Osipenko, O.N. and MacMillan, D. and McFarlane, K.M. and Tate, R.J.S.J. and Kempsill, F.E.J. (2003) Two-pore domain k channel, TASK-1, in pulmonary artery smooth muscle cells. Circulation Research, 93. pp. 957-964. ISSN 0009-7330

Wan, K.F. and Sambi, B.S. and Tate, R. and Waters, C. and Pyne, N.J. (2003) The inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and g-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factor. Journal of Biological Chemistry, 278. pp. 18658-18663. ISSN 0021-9258

Stepek, G and Auchie, M and Tate, R and Watson, K and Russell, D G and Devaney, E and Harnett, W (2002) Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific. Parasitology, 125 (Pt 2). pp. 155-64. ISSN 0031-1820

Connolly, John G. and Tate, Roth J. and McLennan, Neil F. and Brown, Debbie and Telling, Glenn C. and Fraser, Jan and Head, Mark W. (2002) Properties of the cellular prion protein expressed in Xenopus oocytes. NeuroReport, 13 (9). pp. 1229-1233. ISSN 0959-4965

Tate, R. and Arshavsky, V.Y. and Pyne, N.J. (2002) The identification of the inhibitory gamma-subunits of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase in non-retinal tissues: differential processing of mRNA transcripts. Genomics, 79 (4). pp. 582-586. ISSN 1089-8646

Frame, Mhairi and Wan, Kah Fei and Tate, R. and Vandenabeele, Peter and Pyne, Nigel J. (2001) The gamma subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3. Cellular Signalling, 13 (10). pp. 735-741. ISSN 0898-6568

Alderton, F. and Sambi, B.S. and Tate, R. and Pyne, N.J. and Pyne, S. (2001) Assessment of agonism at g-protein coupled receptors by phosphatidic acid and lysophosphatidic acid in human embryonic kidney 293 cells. British Journal of Pharmacology, 134 (1). pp. 6-9. ISSN 0007-1188

Wan, K.F. and Sambi, B.S. and Frame, M.J. and Tate, R. and Pyne, N.J. (2001) The inhibitory gamma subunit of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase is a novel intermediate regulating p42/p44 mitogen-activated protein kinase signaling in human embryonic kidney 293 cells. Journal of Biological Chemistry, 276 (41). pp. 37794-37802. ISSN 0021-9258

Ahmad, M and Abdel-Wahab, Y H and Tate, R and Flatt, P R and Pyne, N J and Furman, B L (2000) Effect of type-selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN-BD11. British Journal of Pharmacology, 129 (6). pp. 1228-1234. ISSN 0007-1188

Osipenko, O N and Tate, R J and Gurney, A M and Tate, Rothwelle (2000) Potential role for kv3.1b channels as oxygen sensors. Circulation Research, 86 (5). pp. 534-40. ISSN 0009-7330

Pyne, S and Rakhit, S and Conway, A M and McKie, A and Darroch, P and Tate, R and Pyne, N (1999) Extracellular actions of sphingosine 1-phosphate through endothelial differentiation gene products in mammalian cells: role in regulating proliferation and apoptosis. Biochemical Society Transactions, 27 (4). pp. 404-409. ISSN 0300-5127

Rakhit, S and Conway, A M and Tate, R and Bower, T and Pyne, N J and Pyne, S (1999) Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase. Biochemical journal, 338 (3). pp. 643-649. ISSN 0264-6021

Tate, R J and Tolan, D and Pyne, S (1999) Molecular cloning of magnesium-independent type 2 phosphatidic acid phosphatases from airway smooth muscle. Cellular Signalling, 11 (7). pp. 515-522. ISSN 0898-6568

Tate, R J and Lochhead, A and Brzeski, H and Arshavsky, V and Pyne, N J (1998) The gamma-subunit of the rod photoreceptor cGMP-binding cGMP-specific PDE is expressed in mouse lung. Cell Biochemistry and Biophysics, 29 (1-2). pp. 133-144. ISSN 1085-9195

Somiari, R I and Brzeski, H and Tate, R and Bieleck, S and Polak, J (1997) Cloning and sequencing of an aspergillus niger gene coding for beta-fructufuranosidase. Biotechnology Letters, 19 (12). pp. 1243-1247. ISSN 0141-5492

Habib, F K and Ross, M and Tate, R and Chisholm, G D (1997) Differential effect of finasteride on the tissue androgen concentrations in benign prostatic hyperplasia. Clinical Endocrinology, 46 (2). pp. 137-44. ISSN 0300-0664

Belham, C M and Tate, R J and Scott, P H and Pemberton, A D and Miller, H R and Wadsworth, R M and Gould, G W and Plevin, R (1996) Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases. Biochemical journal, 320 ( Pt . pp. 939-46. ISSN 0264-6021

Iehlé, C and Délos, S and Guirou, O and Tate, R and Raynaud, J P and Martin, P M (1995) Human prostatic steroid 5 alpha-reductase isoforms--a comparative study of selective inhibitors. Journal of Steroid Biochemistry and Molecular Biology, 54 (5-6). pp. 273-279. ISSN 0960-0760

Heyns, C F and Tate, R and Sargent, N S and Habib, F K and Chisholm, G D (1993) Absence of 5 alpha-reductase activity in the gubernaculum during descent of the fetal pig testis. Journal of Urology, 150 (2 Pt 1). pp. 510-513. ISSN 0022-5347

Book Section

Pyne, N.J. and Murray, Fiona and Tate, R. and MacLean, Margaret R (2006) Molecular Determinants in pulmonary hypertension : Role of PDE5. In: Cyclic nucleotide phosphodiesterases in health and diseases. CRC/Taylor & Francis Group, Boca Raton, pp. 501-518. ISBN 9780849396687

Conference or Workshop Item

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2011) RNA stability in frozen/thawed clinical samples. In: The 6th UK and RI Postgraduate Conference in Biomedical Engineering and Medical Physics, 2011-08-14 - 2011-08-16, Glasgow.

Posada Estefan, Olga Maria and Tate, Rothwelle and Grant, Mary (2011) RNA stability in frozen/thawed clinical blood samples. In: British Toxicology Society Meeting, 2011-09-05 - 2011-09-06, Nottingham.