|Up a level|
Martinez Marcos, Laura and Lamprou, Dimitrios and McBurney, Roy and Halbert, Gavin (2016) A novel hot-melt extrusion formulation of albendazole for increasing dissolution properties. International Journal of Pharmaceutics, 499 (1-2). pp. 175-185. ISSN 0378-5173
Sayin, Ridade and Martinez Marcos, Laura and Osorio, Juan G. and Cruise, Paul and Jones, Ian and Halbert, Gavin W. and Lamprou, Dimitrios A. and Litster, James D. (2015) Investigation of an 11mm diameter twin screw granulator : screw element performance and in-line monitoring via image analysis. International Journal of Pharmaceutics. ISSN 0378-5173
Mather, Stephen J. and Nock, Berthold A. and Maina, Theodosia and Gibson, Vickie and Ellison, David and Murray, Iain and Sobnack, Ravin and Colebrook, Steve and Wan, Susan and Halbert, Gavin and Szysko, Teresa and Powles, Thomas and Avril, Norbert (2014) GRP receptor imaging of prostate cancer using [(99m)Tc]Demobesin 4 : a first-in-man study. Molecular Imaging and Biology, 16 (6). pp. 888-895. ISSN 1860-2002
Kourentas, A and Vertzoni, M and Khadra, Ibrahim and Halbert, Gavin and Clark, Hugh and Butler, James and Reppas, Christos (2014) Albendazole vs. albendazole sulphate in the fasted upper gastrointestinal lumen based on ex vivo and in vitro data. In: American Association of Pharmaceutical Scientists, 2014-11-02 - 2014-11-06, San Diego.
Armstrong, M. and Kreiner, M. and Elliott, M.A. and Halbert, G.W. (2014) Comparative analysis of the physical and chemical properties of new and expired blister pack foils for hard gelatin capsule packaging. In: APS PharmSci 2014, 2014-09-08 - 2014-12-10, University of Hertfordshire.
Kreiner, M. and Armstrong, M. and Elliott, M.A. and Halbert, G.W. (2014) Rheology to guide formulation development of particulate dispersions for automated capsule filling. In: APS PharmSci 2014, 2014-09-08 - 2014-12-10, University of Hertfordshire.
Bergström, Christel A.S. and Holm, René and Jørgensen, Søren Astrup and Andersson, Sara B.E. and Artursson, Per and Beato, Stefania and Borde, Anders and Box, Karl and Brewster, Marcus and Dressman, Jennifer and Feng, Kung-I. and Halbert, Gavin and Kostewicz, Edmund and McAllister, Mark and Muenster, Uwe and Thinnes, Julian and Taylor, Robert and Mullertz, Anette (2014) Early pharmaceutical profiling to predict oral drug absorption : current status and unmet needs. European Journal of Pharmaceutical Sciences, 57. pp. 173-199. ISSN 0928-0987
Etherson, Kelly and Halbert, Gavin and Elliott, Moira (2014) Determination of excipient based solubility increases using the CheqSol method. International Journal of Pharmaceutics, 465 (1-2). pp. 202-209. ISSN 0378-5173
Yip, Kent and Goh, Vicky and Gregory, Jane and Simcock, Ian and Stirling, J. James and Taylor, N. Jane and Kozarski, Robert and Mitchell, Andrew and Bosopem, Sam and Halbert, Gavin and Alonzi, Roberto and Miles, David and Hoskin, Peter (2014) The acute physiological effects of the vaso-active drug, L-NNA, a nitric oxide synthase inhibitor, on renal and tumour perfusion in human subjects. Journal of Cancer Therapy, 5 (1). pp. 44-52.
Horsley, Laura and Cummings, Jeff and Middleton, Mark and Ward, Tim and Backen, Alison and Clamp, Andrew and Dawson, Martin and Farmer, Hayley and Fisher, Nita and Halbert, Gavin and Halford, Sarah and Harris, Adrian and Hasan, Jurjees and Hogg, Philip and Kumaran, Gireesh and Little, Ross and Parker, Geoff J. M. and Potter, Paula and Saunders, Mark and Roberts, Caleb and Shaw, Danielle and Smith, Nigel and Smythe, Jon and Taylor, Andrew and Turner, Helen and Watson, Yvonne and Dive, Caroline and Jayson, Gordon C. and , Cancer Research UK Drug Development Office Phase I clinical tria (2013) A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology, 72 (6). pp. 1343-1352. ISSN 0344-5704
Dick, Lindsay J and Gray, Andrew and Ram, Asha and Hume, Aileen and Parris, Caroline and Hogg, Philip J and Elliott, Moira A and Ford, Steven J and Halbert, Gavin W (2013) Elimination of the antimicrobial action of the organoarsenical cancer therapeutic, 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid, before finished product sterility testing. Journal of Pharmacy and Pharmacology, 65 (11). 1664–1669.
Armstrong, Michelle and Kreiner, Michaela and Elliott, Moira and Halbert, Gavin (2013) Rheological characterisation of formulations for liquid fill hard gelatin capsules. In: APS PharmSci 2013, 2013-09-02 - 2013-09-04, Heriot Watt University.
Halbert, Gavin and Elliott, Moira and Ford, Steven and Dick, Lindsay and Schmidt, Elke (2013) Improved pharmaceutical stability of a boronphenylalanine mannitol formulation for boron neutron capture therapy. European Journal of Pharmaceutical Sciences, 48. pp. 735-739. ISSN 0928-0987
Gray, Andrew and Dick, Lindsay and Elliott, Moira and Ford, Steven and Halbert, Gavin (2012) A comparative analysis of two different analysers used for determination of the Total Organic Carbon in pharmaceutical grade water. European Journal of Parenteral and Pharmaceutical Sciences, 17 (2). pp. 47-51. ISSN 0964-4679
Jorgensen, Heather and Cosimo, Emilio and Elliott, Moira and Michie, Alison and Holyoake, Tessa and Halbert, Gavin and McCaig, Alison (2012) Targeting proliferating CLL cells with a novel synthetic low density lipoprotein drug delivery system. Haematologica, 97 (supple). p. 54. ISSN 0390-6078
Schmidt, Elke and Dooley, Neil and Ford, Steven J. and Elliott, Moira and Halbert, Gavin W. (2012) Physicochemical investigation of the influence of saccharide-based parenteral formulation excipients on l-p-boronphenylalanine solubilisation for boron neutron capture therapy. Journal of Pharmaceutical Sciences, 101 (1). pp. 223-232. ISSN 0022-3549
Gray, Andrew and Dick, Lindsay and Elliott, Moira and Ford, Steven and Halbert, Gavin (2012) Comparative analysis of TOC and conductivity analysers as applied to pharmaceutical water analysis. In: UK Pharm Sci 2012, 2012-09-12 - 2012-09-14.
Dick, Lindsay and Dooley, Neil and Elliott, Moira A and Ford, Steven J and Gordon, Malcolm R and Halbert, Gavin W and Kerr, William J (2011) Boron phenylalanine and related impurities: HPLC analysis, stability profile and degradation pathways. Journal of Pharmaceutical and Biomedical Analysis, 56 (3). pp. 633-636.
Danson, S. J. and Johnson, P. and Ward, T. H. and Dawson, M. and Denneny, O. and Dickinson, G. and Aarons, L. and Watson, A. and Jowle, D. and Cummings, J. and Robson, L. and Halbert, Gavin and Dive, C. and Ranson, M. (2011) Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1. Annals of Oncology, 22 (7). pp. 1653-1660. ISSN 1569-8041
Green, S. and Phoenix, B. and Mill, A. J. and Hill, M. and Charles, M. W. and Thompson, J. and Jones, B. and Ngoga, D. and Detta, A. and James, N. D. and Doran, J. and Graham, N. and Ghani, Z. and Wojnecki, C. and Halbert, G. and Elliott, M. and Ford, S. and Sheehan, T. M. T. and Vickerman, J. and Lockyer, N. and Croswell, G. and Boddy, A. and King, A. and Cruickshank, G. S. (2011) The Birmingham Boron Neutron Capture Therapy (BNCT) project : developments towards selective internal particle therapy. Clinical Oncology, 23 (3). S23-S24. ISSN 0936-6555
Zhou, Peixun and Hatziieremia, Sophia and Elliott, Moira A and Scobie, Linda and Crossan, Claire and Michie, Alison M and Holyoake, Tessa L and Halbert, Gavin W and Jørgensen, Heather G (2010) Uptake of synthetic low density Lipoprotein by leukemic stem cells--a potential stem cell targeted drug delivery strategy. Journal of Controlled Release, 148 (3). pp. 380-387.
Schmidt, E. and Ford, S. and Dooley, N. and Elliot, M. and Halbert, G. (2010) Effects of substituting Fructose by Mannitol in a pharmaceutical formulation. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1428-1429. ISSN 0022-3573
Elliott, M. A. and Schmidt, E. and Ford, S. J. and Halbert, G. W. (2010) Experiences of melt fill production of Fenretinide/Lym-X-Sorb (TM) hard gelatin capsules for Phase I clinical trial. In: UNSPECIFIED.
Dooley, N. and Ford, S. J. and Prasad, Elke and Elliott, M. and Halbert, Gavin (2010) Experimental scrutiny and project timelines : an example. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1208-1209. ISSN 0022-3573
Ngoga, D. G. and Cruickshank, G. and Detta, A. and Green, S. and James, N. D. and Wojnecki, C. and Doran, J. and Graham, N. and Ghani, Z. and Halbert, G. and Elliot, M. and Ford, S. and Braithwaite, R. and Sheehan, T. M. T. and Vickerman, J. and Lockyer, N. and Croswell, G. and Sugar, R. and Boddy, A. (2010) Boron Neutron Capture Therapy (BNCT) : clinical optimization of uptake parameters of Boronophenylalanine (BPA). Neuro-Oncology, 12 (3). p. 62. ISSN 1522-8517
Cruickshank, G.S. and Ngoga, D. and Detta, A. and Green, S. and James, N.D. and Wojnecki, C. and Doran, J. and Halbert, G.W. (2009) A Cancer Research UK pharmacokinetic study of bpa-mannitol in patients with high grade glioma to optimise uptake parameters for clinical trials of BNCT. Applied Radiation and Isotopes, 67 (7-8). S31-S33. ISSN 0969-8043
Lee, C.P. and Payne, G.S. and Oregioni, A, and Ruddle, R. and Tan, S. and Raynaud, F.I. and Eaton, D. and Campbell, M.J. and Cross, K. and Halbert, G.W. and Tracy, M. and McNamara, J. and Seddon, B. and Leach, M.O. and Workman, P. and Judson, I. (2009) A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy. British Journal of Cancer, 101. pp. 1860-1868. ISSN 0007-0920
Halbert, G.W. (2009) The weakest link is getting stronger. European Pharmaceutical Review, 14 (6). pp. 68-72. ISSN 1360-8606
Elliott, Moira and Halbert, G.W. (2008) Maintaining a frozen shipping environment for Phase I clinical trial distribution. International Journal of Pharmaceutics, 346 (1-2). pp. 89-92. ISSN 0378-5173
Steward, W. P. and Middleton, M. and Benghiat, A. and Loadman, P. M. and Hayward, C. and Waller, S. and Ford, S. and Halbert, G. and Patterson, L. H. and Talbot, D. (2007) The use of pharmacokinetic and pharmacodynamic end points to determine the dose of AQ4N, a novel hypoxic cell cytotoxin, given with fractionated radiotherapy in a phase I study. Annals of Oncology, 18 (6). pp. 1098-1103. ISSN 1569-8041
Ranson, Malcolm and Middleton, Mark, R. and Bridgewater, John and Lee, Siow Ming and Dawson, M. and Jowle, Debra and Halbert, G.W. and Waller, Sue and McGrath, Helen and Gumbrell, Lindsey and McElhinney, R. Stanley and Donnelly, Dorothy and McMurry, T. Brian H. and Margison, Geoffrey, P. (2006) Lomeguatrib, a potent inhibitor of o-6-alkylguanine-DNA-alkyltrasnferase: phase i safety, pharmacodynamic, and pharmacokinetic trial and evaluation in combination with temozolomide in patients with advanced solid tumours. Clinical Cancer Research, 12 (5). pp. 1577-1584. ISSN 1557-3265
Halbert, Gavin (2005) Novel salts of AQ4N : BTG +CR UK. .
Elliott, M A and Halbert, G W (2005) Maintaining the cold chain shipping environment for Phase I clinical trial distribution. International Journal of Pharmaceutics, 299 (1-2). pp. 49-54. ISSN 0378-5173
Hayavi, S. and Halbert, G.W. (2005) Synthetic low density lipoprotein, a novel biomimetic LiPID supplement for serum free tissue culture. Biotechnology Progress, 21 (4). pp. 1262-1268. ISSN 8756-7938
Elliott, M. A. and Halbert, G. W. (2004) Verification of a phase I clinical trial distribution network for cold storage materials. [Review]
O'Donnell, A. and Judson, I. and Dowsett, M. and Raynaud, F. and Dearnaley, D. and Mason, M. and Harland, S. and Robbins, A. and Halbert, G.W. and Nutley, B. and Jarman, M. (2004) Hormonal impact of the 17 alpha-hydroxylase/C-17,C-20-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. British Journal of Cancer, 90 (12). pp. 2317-2325. ISSN 0007-0920
Ford, S J and Elliott, M A and Halbert, G W (2003) Use of mathematical derivatives (time-domain differentiation) on chromatographic data to enhance the detection and quantification of an unknown 'rider' peak. Journal of Pharmaceutical and Biomedical Analysis, 33 (4). pp. 563-570. ISSN 0731-7085
Seddon, B.M. and Payne, G.S. and Simmons, L. and Ruddle, R. and Grimshaw, R. and Tan, S. and Turner, A. and Raynaud, F. and Halbert, G.W. and Leach, M.O. and Judson, I. and Workman, P. (2003) A phase I study of SR-4554 via intravenous administration for noninvasive investigation of tumor hypoxia by magnetic resonance spectroscopy in patients with malignancy. Clinical Cancer Research, 9 (14). pp. 5101-12. ISSN 1557-3265
Elliott, M A and Ford, S J and Walker, A A and Hargreaves, R H J and Halbert, G W (2002) Development of a lyophilised RH1 formulation : a novel DT diaphorase activated alkylating agent. Journal of Pharmacy and Pharmacology, 54 (4). pp. 487-492. ISSN 0022-3573
Baillie, G. and Owens, M. and Halbert, G.W. (2002) A synthetic low density lipoprotein particle capable of supporting U937 proliferation in vitro. Journal of Lipid Research, 43. pp. 69-73. ISSN 0022-2275
Halbert, Gavin (1998) Growth Enhanced Properties of a Synthetic Low Density Lipoprotein: "SLDL". .