A microfluidics platform for human tau mutation neurons

Torrance, Emma and Robertson, Graham and Wray, Selina and Hardy, John and Bushell, Trevor and Zagnoni, Michele; (2014) A microfluidics platform for human tau mutation neurons. In: MicroTAS 2014. CBM Society, USA, pp. 898-890. ISBN 9780979806476 (http://www.rsc.org/images/loc/2014/PDFs/Papers/294...)

Abstract

This paper reports a microfluidic approach for assessing network formation in human induced pluripotent stem cell (iPSC)-derived neurons. For the first time, we show the ability of iPSC-derived neurons to form functional synaptically driven networks within a controlled microfluidic environment, thus providing an in vitro stem cell based model for studying dementia.

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• Item metadata

  Item type:	Book Section
  ID code:	53463
  Dates:	Date Event 2014 Published
  Subjects:	Medicine > Internal medicine > Neuroscience. Biological psychiatry. Neuropsychiatry
  Department:	Faculty of Engineering > Electronic and Electrical Engineering Technology and Innovation Centre > Advanced Science and Technology Technology and Innovation Centre > Bionanotechnology Faculty of Engineering > Biomedical Engineering Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	23 Jun 2015 07:39
  Last modified:	08 Apr 2024 13:21
  Related URLs:	Event
  URI:	https://strathprints.strath.ac.uk/id/eprint/53463