Fluorescence nanotomography using resonance energy transfer: Demonstration with a protein-sugar complex

Rolinski, Olaf J. and Birch, David J.S. and McCartney, Lydia J. and Pickup, John C. (2001) Fluorescence nanotomography using resonance energy transfer: Demonstration with a protein-sugar complex. Physics in Medicine and Biology, 46 (2001). N221-N226. ISSN 0031-9155 (http://dx.doi.org/10.1088/0031-9155/46/9/401)

Abstract

A new approach to structural sensing, fluorescence resonance energy transfer nanotomography, which interprets fluorescence decay measurement in terms of site density analysis of molecular distributions, has been applied to a glucose sensor based on competitive binding with malachite green labelled dextran to the sugar binding protein concanavalinA labelled with allophycocyanin. Opportunities for structural sensing in clinical medicine are highlighted.

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• Item metadata

  Item type:	Article
  ID code:	3059
  Dates:	Date Event 22 August 2001 Published
  Subjects:	Science > Physics > Solid state physics. Nanoscience
  Department:	Faculty of Science > Physics
  Depositing user:	Strathprints Administrator
  Date deposited:	27 Mar 2007
  Last modified:	08 Apr 2024 15:21
  URI:	https://strathprints.strath.ac.uk/id/eprint/3059