Micromachined glass apertures for artificial lipid bilayer formation in a microfluidic system

Sandison, Mairi E. and Zagnoni, Michele and Abu-Hantash, Mustafa and Morgan, Hywel (2007) Micromachined glass apertures for artificial lipid bilayer formation in a microfluidic system. Journal of Micromechanics and Microengineering, 17 (7). S189-S196. ISSN 0960-1317 (https://doi.org/doi:10.1088/0960-1317/17/7/S17)

Abstract

The use of spark assisted chemical engraving (SACE) to produce glass apertures that are suitable for the formation of artificial bilayer lipid membranes is described. Prior to use, the glass apertures were rendered hydrophobic by a silanization process and were then incorporated into a simple microfluidic device. Successful bilayer lipid membrane (BLM) formation and the subsequent acquisition of single-channel recordings are demonstrated. Due to the simplicity and rapidity of the SACE process, these glass apertures could be easily integrated into an all-glass microfluidic system for BLM formation.

• Share and Export
  

  RDF+XMLBibTeXRIOXX2 XMLRDF+N-TriplesJSONDublin CoreAtomSimple MetadataReferMETSHTML CitationASCII CitationOpenURL ContextObjectEndNoteOpenURL ContextObject in SpanMODSMPEG-21 DIDLEP3 XMLData Cite XMLRIS (EndNote Online, Zotero, Ref manager, etc)RDF+N3Multiline CSV
• Item metadata

  Item type:	Article
  ID code:	29056
  Dates:	Date Event 2 July 2007 Published
  Subjects:	Technology > Electrical engineering. Electronics Nuclear engineering
  Department:	Faculty of Engineering > Electronic and Electrical Engineering Faculty of Engineering > Biomedical Engineering
  Depositing user:	Pure Administrator
  Date deposited:	25 Mar 2011 11:23
  Last modified:	08 Apr 2024 18:49
  URI:	https://strathprints.strath.ac.uk/id/eprint/29056