Simulation of deposit formation in particle laden flows: thermal properties

Mulholland, A.J. (2003) Simulation of deposit formation in particle laden flows: thermal properties. Biomedicine and Pharmacotherapy, 56 (7). p. 347. ISSN 0753-3322 (http://dx.doi.org/10.1016/S0753-3322(02)00244-5)

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Abstract

Fatty deposits formed on arterial walls lead to atherosclerosis but it is the interplay between these deposits and the vessel walls which governs the growth of plaque formation. Cells in the vessel walls trigger the body's defenses and through a series of mechanisms lead to the promotion of plaque growth. Crucially however the vast majority of acute coronary syndromes such as, myocardial infarction, and sudden ischaemic cardiac death is caused by atherosclerotic plaque rupture and not from a stenosis growing and blocking the blood flow. Although the stress caused by the blood flow does play a role in plaque rupture, it has been found that the degree of stenosis is a relatively minor factor in predicting which plaques are most prone to rupture. In fact, atherosclerotic plaques expand into the vessel wall during much of their existence and this can make their detection problematic.

  • Item type:Article
    ID code:2131
    Dates:
    Date
    Event
    2003
    Published
    Notes:Progress in Bioengineering and the Vascular Endothelium: Basic and Clinical Aspects Fourth International Congress. September 30-October 1, 2002, Pisa, Italy.
    Subjects:Science > Mathematics
    Department:Faculty of Science > Mathematics and Statistics
    Depositing user: Strathprints Administrator
    Date deposited:23 Nov 2006
    Last modified:08 Apr 2024 15:26
    URI:https://strathprints.strath.ac.uk/id/eprint/2131
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