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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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The effect of pulsed bipolar dc on the simultaneous extraction of glucose and lactate by reverse iontophoresis

Ching, C.T.S. and Buisson, Y. and Connolly, P. (2008) The effect of pulsed bipolar dc on the simultaneous extraction of glucose and lactate by reverse iontophoresis. Sensors and Actuators B: Chemical, 129 (2). pp. 504-509. ISSN 0925-4005

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Abstract

This in vitro study focused on the investigation of the effect of current waveform on simultaneous glucose and lactate extraction by reverse iontophoresis. Experiments were performed using diffusion cells. An iontophoretic current (0.3 mA cm−2) at four different current waveforms (a combination of 0-, 5-, 10- and 15-s pulse intervals and 15-min polarity reversal intervals) were applied for 90 min via Ag/AgCl electrodes. Glucose and lactate extraction were quantified by spectrometric analysis. The result suggests that extraction of glucose and lactate by pulsed bipolar current are pulse-frequent dependent and pulsed bipolar current at a particular pulse-frequent is found to be more effective on glucose and lactate extraction than bipolar current.