Kosmidis, K. and Russell, Christopher D. and Dobre, George and Podoleanu, Adrian Gh. and Black, R.A. (2007) Flying spot en face OCT for monitoring cell distribution in collagen-based constructs. Multiphoton Microscopy in the Biomedical Sciences IV (Proceedings of SPIE), 6079. 60790Q-1. ISSN 1605-7422
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
The use of optical coherence tomography (OCT) as a monitoring tool in the growth of human fibroblasts cells in collagen-based constructs is investigated. Rat-tail tendon type-1 collagen based gels mixed with human fibroblasts were prepared and incubated. Fixed samples were then imaged using OCT, and subsequently cross-sectioned and analysed microscopically. The concentration of cells in samples under different contraction dynamics was investigated using analysis of the OCT images. Results show clear differences in scattering intensity as a consequence of cell concentration in both OCT images and micrographs.
| Item type: | Article |
|---|---|
| ID code: | 8331 |
| Notes: | Biomedical Optics Conference, San Jose, 21-26 Jan. 2006 Progress in Biomedical Optics and Imaging, Vol. 7, No. 2, 2006 |
| Keywords: | optical coherence tomography, collagen gels, cell distribution, tissue engineering, Bioengineering, Physiology |
| Subjects: | Technology > Engineering (General). Civil engineering (General) > Bioengineering Science > Physiology |
| Department: | Faculty of Engineering > Bioengineering |
| Related URLs: | |
| Depositing user: | Strathprints Administrator |
| Date Deposited: | 04 Aug 2009 15:33 |
| Last modified: | 04 Oct 2012 12:36 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/8331 |
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