Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Micro-LED arrays: a tool for two-dimensional neuron stimulation

Poher, V. and Grossman, N. and Kennedy, G.T. and Nikolic, K. and Zhang, H.X. and Gong, Z. and Drakakis, E.M. and Gu, E. and Dawson, M.D. and French, P.M.W. and Degenaar, P. and Neil, M.A.A. (2008) Micro-LED arrays: a tool for two-dimensional neuron stimulation. Journal of Physics D: Applied Physics, 41 (9). 094014. ISSN 0022-3727

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Stimulating neuron cells with light is an exciting new technology that is revolutionizing the neurosciences. To date, due to the optical complexity that is involved, photostimulation has only been achieved at a single site using high power light sources. Here we present a GaN based micro-light emitting diode (LED) array that can open the way to multi-site photostimulation of neuron cells. The device is a two-dimensional array of micrometre size LED emitters. Each emitter has the required wavelength, optical power and modulation bandwidth to trigger almost any photosensitizer and is individually addressable. We demonstrate micrometre resolution photoactivation of a caged fluorophore and photostimulation of sensitized living neuron cells. In addition, a complete system that combines the micro-LED array with multi-site electrophysiological recording based on microelectrode array technology and/or fluorescence imaging is presented.

Item type: Article
ID code: 7786
Keywords: micro-LED arrays, neuron stimulation, LED, neuron cells, neurosciences, photostimulation, optics, Optics. Light
Subjects: Science > Physics > Optics. Light
Department: Faculty of Science > Institute of Photonics
Related URLs:
Depositing user: Miss Sharon Kelly
Date Deposited: 15 Dec 2009 16:12
Last modified: 16 Jul 2013 21:15
URI: http://strathprints.strath.ac.uk/id/eprint/7786

Actions (login required)

View Item