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Pharmacokinetics of drugs in liver disease

Johnson, T.N. and Thomson, A.H. (2008) Pharmacokinetics of drugs in liver disease. In: Drugs and the Liver: A guide to drug handling in liver dysfunction. Pharmaceutical Press, pp. 103-135. ISBN 978-0-85369-710-7

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Abstract

Liver disease is a widespread and increasing problem throughout the world, however little is published on how different types and degrees of liver dysfunction affect the body's ability to handle medicines. This chapter examines the pharmacokinetics of drugs in liver disease.