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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Anti-Acanthamoeba efficacy in contact lens disinfecting systems

Beattie, T.K. and Tomlinson, A. and Seal, D. (2002) Anti-Acanthamoeba efficacy in contact lens disinfecting systems. British Journal of Ophthalmology, 86 (11). pp. 1310-1320. ISSN 0007-1161

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Abstract

Hiti et al produced an interesting study investigating the susceptibility of three strains of Acanthamoeba to a PHMB (polyhexamethylene biguanide) based multipurpose solution (MPS), a one step peroxide system (3% H2O2), and a two step peroxide system (0.6% H2O2). However, no comment was made regarding the choice of strains tested, only one of which (A castellanii 4CL) was typical of those that cause keratitis in humans. Although testing of all three strains was of interest to the microbiologist, the only result that can be extrapolated to clinical practice and be of clinical relevance to the contact lens wearer is that for A castellanii (4CL).