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Growth and viability of osteoblasts on hydroxyapatite and tri-calcium phosphate ceramics: the effect of collagen coating

Ball, A.J. and Rodgers, E.H. and Goldie, E.I. and Connel, G. and Savage, R. and Hamblin, J. and Grant, M.H. (2002) Growth and viability of osteoblasts on hydroxyapatite and tri-calcium phosphate ceramics: the effect of collagen coating. European Cells and Materials, 4 (2). p. 57. ISSN 1473-2262

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Abstract

Summary of paper describing how Hydroxyapatite (HA) and tricalcium phosphate (TCP) ceramics form the basis for bioartificial bone replacement materials. They lack mechanical strength and cannot at present be considered as replacements for loadbearing areas. We have investigated the characteristics of two ceramic materials, HA and a 60:40 composite of HA:TCP, which are being developed for facial bone reconstruction. The growth and viability of an immortalized cell line, FFC, derived from neonatal rat calvaria, was investigated when cultured on the materials for 7 days.