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Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Modulation of soleus H-reflex following ipsilateral mechanical loading of the sole of the foot in normal and complete spinal cord injured humans

Knikou, M. and Conway, B.A. (2001) Modulation of soleus H-reflex following ipsilateral mechanical loading of the sole of the foot in normal and complete spinal cord injured humans. Neuroscience Letters, 303 (2). pp. 107-110. ISSN 0304-3940

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Abstract

The modulation of the soleus H-reflex in response to tonic mechanical loading applied to the plantar aspect of the foot sole was examined in nine normal subjects and five patients with a clinically defined complete spinal cord injury (SCI). With the subjects seated, tonic pressure applied to the metatarsal region of the ipsilateral foot sole significantly depressed soleus H-reflex excitability in all subjects. The demonstration of a decrease in H-reflex excitability in both subject groups as a result of applied pressure to the foot suggests that the change in reflex excitability is the result of a common spinal mechanism. The results highlight the modulatory effects that natural stimulation of cutaneous afferents can have on reflex excitability and may have practical application in gait rehabilitation and in the management of disorders of muscle tone following SCI.