Reversible DNA micro-patterning using the fluorous effect

Flynn, Gabriella and Withers, Jamie and Macias, Gerard and Sperlin, Justin R. and Henry, Sarah L. and Cooper, Jonathan M. and Burley, Glenn A. and Clark, Alasdair W. (2017) Reversible DNA micro-patterning using the fluorous effect. Chemical Communications, 53 (21). pp. 3094-3097. ISSN 1359-7345 (https://doi.org/10.1039/C7CC00288B)

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Abstract

We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.

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• Item metadata

  Item type:	Article
  ID code:	60144
  Dates:	Date Event 23 February 2017 Published 15 February 2017 Accepted
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry Technology and Innovation Centre > Bionanotechnology
  Depositing user:	Pure Administrator
  Date deposited:	13 Mar 2017 09:35
  Last modified:	08 Apr 2024 23:24
  Related URLs:	Related item
  URI:	https://strathprints.strath.ac.uk/id/eprint/60144