Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.


A transition arm modular multilevel universal pulse-waveform generator for electroporation applications

Elgenedy, Mohamed A. and Badawy, Ahmed and Ahmed, Shehab and Williams, Barry W. (2017) A transition arm modular multilevel universal pulse-waveform generator for electroporation applications. IEEE Transactions on Power Electronics. pp. 1-13. ISSN 0885-8993 (In Press)

Text (Elgenedy-etal-ITPE2017-A-transition-arm-modular-multilevel-universal-pulse-waveform-generator)
Elgenedy_etal_ITPE2017_A_transition_arm_modular_multilevel_universal_pulse_waveform_generator.pdf - Accepted Author Manuscript

Download (2MB) | Preview


High voltage (HV) pulses are used in electroporation to subject pulsed electric field (PEF) onto a sample under treatment. Pulse-waveform shape, voltage magnitude, pulse duration, and pulse repetition rate are the basic controllable variables required for particular PEF application. In practice, a custom-made pulse generator is dedicated for each PEF application with limited flexibility in changing these variables. In this paper, a universal pulse-waveform generator (UPG) is proposed, where the controller software-algorithm can manipulate a basic generated multilevel pulse-waveform to emulate many different PEF pulse-waveforms. The commonly used PEF HV pulse-waveforms can be generated as bipolar or monopolar with controllable pulse durations, repetition times, and voltage magnitudes. The UPG has the ability to generate multilevel pulses that have controllable dv/dt which allow reduction of the electromagnetic interference (EMI) generated by the converter. The UPG topology is based on half-bridge modular multilevel converter (HB-MMC) cells forming two transition arms in conjunction with two bi-state arms, together creating an H-bridge. The HB-MMC cell-capacitors provide a controllable energy source which charge from the dc input supply and discharge across the load, while the two bi-state arms allow charging the HB-MMC cell-capacitors. Hence, the UPG topology offers modularity, redundancy, and scalability. The HB-MMC individual cell-capacitance is low and the cell-voltages are balanced by employing the sorting and rotating algorithm used in conventional HB-MMC topologies for HVDC transmission applications. The viability of the proposed UPG converter is validated by MATLAB/Simulink simulation and scaled-down experimentation.