Bridle, Helen and Wang, Wenxing and Gavriilidou, Despoina and Amalou, Farid and Hand, Duncan P. and Shu, Wenmiao (2016) Static mode microfluidic cantilevers for detection of waterborne pathogens. Sensors and Actuators A: Physical, 247. pp. 144-149. ISSN 0924-4247
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This paper reports on the first demonstration of polymeric microfluidic cantilever sensors. Microcantilever sensors, magnetic beads, and microfluidic technology have been combined to create a polymer based biosensor. Using cheap materials like polyimide, a simple fabrication method has been developed to produce cantilevers with an embedded microfluidic channel. The advantage of this approach is that the addition of a microfluidic channel enables the analysis of smaller volumes and increases the capture efficiency in applications detecting rare analytes. As a proof of principle the system has been applied for the detection of the waterborne protozoan parasite Cryptosporidium, achieving sensitivity comparable to QCM, whereas a previous set-up without the microfluidic channel was unable to detect the parasite.
|Keywords:||microfluidics, cantilever, cryptosporidium, detection, Bioengineering, Bioengineering|
|Subjects:||Technology > Engineering (General). Civil engineering (General) > Bioengineering|
|Department:||Faculty of Engineering > Biomedical Engineering|
|Depositing user:||Pure Administrator|
|Date Deposited:||21 Jul 2016 14:55|
|Last modified:||30 Apr 2017 01:30|