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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by Strathclyde researchers from the Department of Computer & Information Sciences involved in researching exciting new applications for mobile and smartphone technology. But the transformative application of mobile technologies is also the focus of research within disciplines as diverse as Electronic & Electrical Engineering, Marketing, Human Resource Management and Biomedical Enginering, among others.

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Real-time multimodal imaging of nanoparticle-cell interactions in high-throughput microfluidics

Cunha Matos, C.A. and Millington, O.M. and Wark, A. W. and Zagnoni, M. (2014) Real-time multimodal imaging of nanoparticle-cell interactions in high-throughput microfluidics. In: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014). CBM Society, San Diego, CA., pp. 968-970. ISBN 9781634396974

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Abstract

We present an interdisciplinary approach that allows for the evaluation of nanoparticle cytotoxicity at the single-cell level. By combining single-cell microfluidics with nanoparticle chemistry, real-time and high-throughput multimodal imaging of cellular interactions with functionalised gold nanorods was successfully achieved. The integration of such techniques into tools for high-resolution cell monitoring and drug screening has, to the best of our knowledge, not been reported.