Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

Explore

A new molecularly imprinted polymer for the selective extraction of naproxen from urine samples by solid-phase extraction

Caro, E. and Marce, R.M. and Cormack, P.A.G. and Sherrington, D.C. and Borrull, F. (2004) A new molecularly imprinted polymer for the selective extraction of naproxen from urine samples by solid-phase extraction. Journal of Chromatography B, 813 (1-2). pp. 137-143. ISSN 1570-0232

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

A non-covalent molecularly imprinted polymer (MIP) was synthesised using naproxen (a non-steroidal, anti-inflammatory drug (NSAID)) as a template molecule. The NIT was chromatographically evaluated to confirm the imprinting effect, and was then applied as a selective sorbent in solid-phase extraction (SPE) to selectively extract naproxen. After this study, the NIT was used to extract naproxen from urine samples; it was demonstrated that by applying a selective washing step with acetonitrile (ACN) the compounds in the sample that were structurally related to naproxen could be eliminated.