Picture of aircraft jet engine

Strathclyde research that powers aerospace engineering...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by Strathclyde researchers involved in aerospace engineering and from the Advanced Space Concepts Laboratory - but also other internationally significant research from within the Department of Mechanical & Aerospace Engineering. Discover why Strathclyde is powering international aerospace research...

Strathprints also exposes world leading research from the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

Discover more...

A new molecularly imprinted polymer for the selective extraction of naproxen from urine samples by solid-phase extraction

Caro, E. and Marce, R.M. and Cormack, P.A.G. and Sherrington, D.C. and Borrull, F. (2004) A new molecularly imprinted polymer for the selective extraction of naproxen from urine samples by solid-phase extraction. Journal of Chromatography B, 813 (1-2). pp. 137-143. ISSN 1570-0232

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

A non-covalent molecularly imprinted polymer (MIP) was synthesised using naproxen (a non-steroidal, anti-inflammatory drug (NSAID)) as a template molecule. The NIT was chromatographically evaluated to confirm the imprinting effect, and was then applied as a selective sorbent in solid-phase extraction (SPE) to selectively extract naproxen. After this study, the NIT was used to extract naproxen from urine samples; it was demonstrated that by applying a selective washing step with acetonitrile (ACN) the compounds in the sample that were structurally related to naproxen could be eliminated.