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Open Access research with a real impact on health...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Galactosylated poly(ethylene glycol) as a scaffold for primary hepatocytes.

Hamilton, C and Henderson, C J and Ulijn, R V and Grant, M H (2012) Galactosylated poly(ethylene glycol) as a scaffold for primary hepatocytes. European Cells and Materials, 23 (Suppl ). p. 30. ISSN 1473-2262

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Abstract

Maintaining stable cultures of viable and metabolically active primary hepatocytes is a long standing problem 1. Synthetic biomaterials with tuneable chemical properties may provide a suitable platform for the culture of primary cells. Hepatocytes are capable of binding terminal galactose residues via the hepatocyte asialoglycoprotein receptor (ASGPr); targeting of this receptor may facilitate binding of cells, influence morphology and ultimately improve cellular function 2