Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

Explore

Effect of cultured rat primary hepatocytes on the mechanical properties of collagen gel matrices

Agbekoh, Peter E. and Henderson, Catherine and Riches, Philip E. and Grant, M. Helen (2014) Effect of cultured rat primary hepatocytes on the mechanical properties of collagen gel matrices. European Cells and Materials, 28 (S.4). p. 77. ISSN 1473-2262

[img] PDF (Agbekoh-etal-eCM2014-effect-of-cultured-rat-primary-hepatoytes)
Agbekoh_etal_eCM2014_effect_of_cultured_rat_primary_hepatoytes.pdf - Final Published Version

Download (34kB)

Abstract

Collagen gels are widely used as matrices for in vitro cell culture and also for a variety of tissue engineering applications. The mechanical properties of matrices have been shown to be important parameters which greatly influence cell behaviour. For successful support of long term cell growth and function, it is important for matrices to retain their mechanical integrity during the period of use. The presence of cells has been shown to alter matrix properties. The aim of this study was to investigate the effect of seeding primary hepatocytes on the mechanical properties of collagen hydrogel matrices.