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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.


A comparative study of secondary ion yield from model biological membranes using Aun + and C60 + primary ion sources

Baker, M. J. and Fletcher, J. S. and Jungnickel, H. and Lockyer, N. P. and Vickerman, J. C. (2006) A comparative study of secondary ion yield from model biological membranes using Aun + and C60 + primary ion sources. Applied Surface Science, 252 (19). pp. 6731-6733. ISSN 0169-4332

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Aun+ and C60+ primary ion sources have been used to acquire spectra from phospholipids, symmetric liposomes and asymmetric liposomes. We demonstrate that when using different ion beams different chemical information can be obtained. Symmetric and asymmetric liposomes, with 95% asymmetry, were produced and analysed with Au+, Au3+ and C60+ primary ion beams. C60+ gave the greatest yield from the symmetric liposome but after correcting for the yield effects on the data obtained from the asymmetric liposome it has been shown that C60+ is the most surface sensitive, providing the least information from the inner leaflet of the liposome. Aun+ provides the greatest amount of information from the inner leaflet. The results present the possibility of designing ToF-SIMS experiments that selectively probe specific regions of a (bio)molecular surface.