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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

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Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines

Edrada-Ebel, Ruangelie and Wray, V and Witte, L and van Ofwegen, L and Proksch, P (2000) Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines. Zeitschrift fur Naturforschung C, 55 (1-2). pp. 82-86. ISSN 0939-5075

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Abstract

A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-alpha-muurolene (1) and a novel derivative (+)-6-hydroxy-alpha-muurolene (2), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic (1H, 13C, COSY, 1H-detected direct and long range 13C-1H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.