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Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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First report of cryptosporidiosis in paediatric patients in Swaziland

Dlamini, M.S. and Nkambule, S. and Grimason, A.M. (2005) First report of cryptosporidiosis in paediatric patients in Swaziland. International Journal of Environmental Health Research, 15 (5). pp. 393-396. ISSN 0960-3123

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Abstract

Diarrhoeal disease is a significant cause of morbidity and mortality in many African countries, especially among the immunocompromised and the under five population. Over the last decade, the protozoan parasite Cryptosporidum spp. has been shown to be a significant cause of gastro-enetritis in the immunocompetent and immunocompromised in both the developed and developing world. This study reports the first finding of Cryptosporidum spp. oocysts in 2 of 48 (4.2%) faecal samples obtained from Swazi paediatric outpatients (two year old male and three year old female), presenting with diarrhoea at Mbabane Government Hospital between the months July - August 2003. Oocysts were detected using a standard anti-Cryptosporidium immunofluorescence and nuclear staining technique (after formal-ether concentration). Oocysts ranged in size from 4 - 6 µm with between 1 - 4 oocysts per field of view (× 400). The precise species was not determined. Further studies are required to determine the public health significance of Cryptospoirdium in Swaziland.