Picture of smart phone in human hand

World leading smartphone and mobile technology research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by Strathclyde researchers from the Department of Computer & Information Sciences involved in researching exciting new applications for mobile and smartphone technology. But the transformative application of mobile technologies is also the focus of research within disciplines as diverse as Electronic & Electrical Engineering, Marketing, Human Resource Management and Biomedical Enginering, among others.

Explore Strathclyde's Open Access research on smartphone technology now...

Micromachined scaffolds as primers for cartilage growth

Angeli, F. and Connolly, P. and Uttamchandani, D.G. (2006) Micromachined scaffolds as primers for cartilage growth. Micro and Nano Letters, 1 (2). pp. 66-70. ISSN 1750-0443

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

Research on the growth and monitoring of cartilage cells in a controlled microstructured environment is important because of the consideration of how the microenvironment affects the cells involved in cartilage regeneration has been neglected to date. An experimental realisation has been demonstrated of biocompatible microstructured surfaces of controlled topography, which have been formed in biocompatible polyimide (Kapton) and in synthetic bioresorbable, epsilon-polycaprolactone (PCL). Bovine cartilage cell growth has been achieved in vitro on the microstructured surfaces and the retention of chondrocytic morphology has been investigated. The results demonstrate that PCL and Kapton microgrooved surfaces can act as primers for cartilage regeneration and repair in vitro or potentially in vivo, by retaining chondrocytic phenotype and enhancing cartilage formation.