Miller, J. and Wilson, W.S. and Kek, W.K. and Wilson, C.G. and Uttamchandani, D.G. (2003) Spectroscopic detection of a therapeutic drug in the mammalian eye. IEEE Journal of Selected Topics in Quantum Electronics, 9 (2). pp. 171-176. ISSN 1077-260X
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
We have developed a novel and fast ocular spectrometer and demonstrated its ability to perform real time spectroscopic measurements in the mammalian eye. The instrument comprises a hand-held sensor head which, when placed on the cornea, effectively turns the anterior chamber into a cuvette. This sensor head is connected to the rest of the instrument via two optical fibers. Ex vivo and in vivo evaluation demonstrated the ability of the instrument to detect compounds via both absorption and fluorescence spectroscopy. In vivo evaluation demonstrated the ability of the instrument to detect brimonidine in the cornea and aqueous humor of rabbit eyes.
| Item type: | Article |
|---|---|
| ID code: | 4784 |
| Keywords: | contact lens design, intraocular drug detection, ophthalmic instrumentation, optoelectronic instrumentation, spectroscopy, Electronic computers. Computer science |
| Subjects: | Science > Mathematics > Electronic computers. Computer science |
| Department: | ?? 12211 ?? Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Faculty of Engineering > Electronic and Electrical Engineering |
| Related URLs: | |
| Depositing user: | Strathprints Administrator |
| Date Deposited: | 15 Nov 2007 |
| Last modified: | 04 Oct 2012 12:07 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/4784 |
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