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Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Exploiting Hessian matrix and trust-region algorithm in hyperparameters estimation of Gaussian process

Zhang, Y. and Leithead, W.E. (2005) Exploiting Hessian matrix and trust-region algorithm in hyperparameters estimation of Gaussian process. Applied Mathematics and Computation, 171 (2). pp. 1264-1281. ISSN 0096-3003

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Abstract

Gaussian process (GP) regression is a Bayesian non-parametric regression model, showing good performance in various applications. However, it is quite rare to see research results on log-likelihood maximization algorithms. Instead of the commonly used conjugate gradient method, the Hessian matrix is first derived/simplified in this paper and the trust-region optimization method is then presented to estimate GP hyperparameters. Numerical experiments verify the theoretical analysis, showing the advantages of using Hessian matrix and trust-region algorithms. In the GP context, the trust-region optimization method is a robust alternative to conjugate gradient method, also in view of future researches on approximate and/or parallel GP-implementation.