French, N.P. and Kelly, L.A. and Kosmider, R.D. and Clancy, D. (2002) Dose-response relationships for Foot and Mouth disease in cattle and sheep. Infection and Epidemiology, 128. pp. 325-332. ISSN 0950-2688
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
The relationships between the inhaled dose of foot and mouth disease virus and the outcomes of infection and disease were examined by fitting dose-response models to experimental data. The parameters for both the exponential and beta-poisson models were estimated using maximum likelihood and Bayesian methods. The median probability of infection given a single inhaled TCID50 was estimated to be 0·031 with 95% Bayesian credibility intervals (CI) of 0·018-0·052 for cattle, and 0·045 (CI = 0·024-0·080) for sheep. These estimates were used to construct dose-response curves and uncertainty distributions for use in quantitative risk assessments.
| Item type: | Article |
|---|---|
| ID code: | 4583 |
| Keywords: | mathematics, statistics, modelling science, biology, disease, risk assessment, Probabilities. Mathematical statistics, Biology |
| Subjects: | Science > Mathematics > Probabilities. Mathematical statistics Science > Natural history > Biology |
| Department: | Faculty of Science > Mathematics and Statistics |
| Related URLs: | |
| Depositing user: | Strathprints Administrator |
| Date Deposited: | 05 Nov 2007 |
| Last modified: | 04 Oct 2012 12:04 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/4583 |
Actions (login required)
| View Item |