French, N.P. and Kelly, L.A. and Kosmider, R.D. and Clancy, D. (2002) *Dose-response relationships for Foot and Mouth disease in cattle and sheep.* Infection and Epidemiology, 128. pp. 325-332. ISSN 0950-2688

## Abstract

The relationships between the inhaled dose of foot and mouth disease virus and the outcomes of infection and disease were examined by fitting dose-response models to experimental data. The parameters for both the exponential and beta-poisson models were estimated using maximum likelihood and Bayesian methods. The median probability of infection given a single inhaled TCID50 was estimated to be 0·031 with 95% Bayesian credibility intervals (CI) of 0·018-0·052 for cattle, and 0·045 (CI = 0·024-0·080) for sheep. These estimates were used to construct dose-response curves and uncertainty distributions for use in quantitative risk assessments.

Item type: | Article |
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ID code: | 4583 |

Keywords: | mathematics, statistics, modelling science, biology, disease, risk assessment, Probabilities. Mathematical statistics, Biology |

Subjects: | Science > Mathematics > Probabilities. Mathematical statistics Science > Natural history > Biology |

Department: | Faculty of Science > Mathematics and Statistics Faculty of Science > Mathematics and Statistics > Statistics and Modelling Science |

Related URLs: | |

Depositing user: | Strathprints Administrator |

Date Deposited: | 05 Nov 2007 |

Last modified: | 04 Oct 2012 12:04 |

URI: | http://strathprints.strath.ac.uk/id/eprint/4583 |

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