Picture of two heads

Open Access research that challenges the mind...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

Discover more...

Animal growth promoters: to ban or not to ban? A risk assessment approach

Kelly, L.A. and Smith, D.L. and Snary, E.L. and Johnson, J.A. and Harris, A.D. and Wooldridge, M. and Morris, J.G. (2004) Animal growth promoters: to ban or not to ban? A risk assessment approach. International Journal of Antimicrobial Agents, 24 (3). pp. 205-212. ISSN 0924-8579

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

The use of antibiotics for animal growth promotion has been controversial because of the potential transfer of antibiotic resistance from animals to humans. Such transfer could have severe public health implications in that treatment failures could result. We have followed a risk assessment approach to evaluate policy options for the streptogramin-class of antibiotics: virginiamycin, an animal growth promoter, and quinupristin/dalfopristin, a antibiotic used in humans. Under the assumption that resistance transfer is possible, models project a wide range of outcomes depending mainly on the basic reproductive number (R0) that determines the potential for person-to-person transmission. Counter-intuitively, the benefits of a ban on virginiamycin were highest for intermediate values of R0, and lower for extremely high or low values of R0.