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Portable instrument for in-vivo infrared oxymetry using spread-spectrum modulation

Trevisan, Stefano and Bavera, Matteo and Giardini, Mario Ettore (2007) Portable instrument for in-vivo infrared oxymetry using spread-spectrum modulation. Journal of Instrumentation, 2. ISSN 1748-0221

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Near Infrared Spectroscopy (NIRS) can be employed to monitor noninvasively and continuously local changes in hemodynamics and oxygenation of human tissues. A portable NIRS research-grade acquisition system, dedicated to measurements during muscular exercise, is presented. The instrument is able to control up to eight LED sources and two detectors. A digital correlation technique, implemented on a single-chip RISC microcontroller, performs source-to-detector multiplexing. Such algorithm is highly optimized for computational efficiency and ambient noise rejection. Software-configurable input stages allow for flexibility in instrument setup. As a result of the specific correlation technique employed, the instrument is compact, lightweight and efficient. Clinical tests on oxygen consumption show excellent performance.