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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Population pharmacokinetics of tobramycin in patients with and without cystic fibrosis

Hennig, Stephanie and Stanning, Joseph and Staatz, Christine and Thomson, Alison (2013) Population pharmacokinetics of tobramycin in patients with and without cystic fibrosis. Clinical Pharmacokinetics, 52 (4). pp. 289-301. ISSN 0312-5963

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Abstract

While several studies have examined the pharmacokinetics of tobramycin in patients with cystic fibrosis (CF), there is no consensus on whether they differ in patients with and without CF. The objectives of this study were to identify covariates which explain pharmacokinetic variability and to examine whether having the disease CF in itself alters these relationships and drug dose requirements.