Li, Chenhao and Sutter, Jens and Birch, David and Chen, Yu (2012) Fluorescence anisotropy of protein - gold nanoclusters. In: 2012 12th IEEE Conference on Nanotechnology. IEEE Conference Proceedings, New York. ISBN 9781467322003
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1109/NANO.2012.6322067
Abstract
Red-emitting gold nanoclusters (BSA-Au-25) have been synthesized in Bovine Serum albumin and found to have a characteristic fluorescence lifetime of 1.25 mu s. Fluorescence anisotropy measurements of BSA-Au-25 reveal a dramatic increase in protein size as the pH is reduced from 7 to 3.1, consistent with the change of BSA from N form to E form. This study suggests the possibility of exploiting fluorescent protein-gold nanoclusters to probe protein conformational changes in response to the local environment.
| Item type: | Book Section |
|---|---|
| ID code: | 42287 |
| Keywords: | gold nanoclusters, fluorescence anisotropy, BSA, protein conformational change , color , proteins , probes, green products , gold, fluorescence, detectors, Physics |
| Subjects: | Science > Physics |
| Department: | Faculty of Science > Physics |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 05 Dec 2012 14:42 |
| Last modified: | 05 Dec 2012 14:42 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/42287 |
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