Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Fluorescence anisotropy of protein - gold nanoclusters

Li, Chenhao and Sutter, Jens and Birch, David and Chen, Yu (2012) Fluorescence anisotropy of protein - gold nanoclusters. In: 2012 12th IEEE Conference on Nanotechnology. IEEE, New York. ISBN 9781467322003

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Red-emitting gold nanoclusters (BSA-Au-25) have been synthesized in Bovine Serum albumin and found to have a characteristic fluorescence lifetime of 1.25 mu s. Fluorescence anisotropy measurements of BSA-Au-25 reveal a dramatic increase in protein size as the pH is reduced from 7 to 3.1, consistent with the change of BSA from N form to E form. This study suggests the possibility of exploiting fluorescent protein-gold nanoclusters to probe protein conformational changes in response to the local environment.

Item type: Book Section
ID code: 42287
Keywords: gold nanoclusters, fluorescence anisotropy, BSA, protein conformational change , color , proteins , probes, green products , gold, fluorescence, detectors, Physics
Subjects: Science > Physics
Department: Faculty of Science > Physics
Technology and Innovation Centre > Bionanotechnology
Related URLs:
    Depositing user: Pure Administrator
    Date Deposited: 05 Dec 2012 14:42
    Last modified: 09 May 2014 05:26
    URI: http://strathprints.strath.ac.uk/id/eprint/42287

    Actions (login required)

    View Item