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Stereocontrolled access to optically-enriched oxabispidines

Brice, Heloise and Gill, Duncan M and Goldie, Laura and Keegan, Philip S and Kerr, William and Svensson, Per H (2012) Stereocontrolled access to optically-enriched oxabispidines. Chemical Communications, 48 (40). pp. 4836-4838. ISSN 1359-7345

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Abstract

A range of chiral, optically-enriched bicyclic oxabispidines were prepared from (S)-(-)-2,3-epoxypropylphthalimide using an efficient sequence featuring a stereocontrolled intramolecular Mannich reaction as the key transformation.