Zhang, Y. and Yu, J. and Birch, D. J. S. and Chen, Y. (2011) Gold nanorods for applications in biological imaging. [Proceedings Paper]Full text not available in this repository. (Request a copy from the Strathclyde author)
Two-Photon luminescence (TPL) from gold nanorods shows considerable potential in biological imaging for high resolution, low photo-damage, tunable near infra-red (NIR) longitudinal band, polarization dependence, ability to conjugate to bio-molecules and low toxicity. Here we demonstrate the application of gold nanorods as TPL imaging agents by studying the gold nanorods taken up by Madin-Darby canine kidney (MDCK) cells using both confocal imaging and fluorescence lifetime imaging microscopy (FLIM). The characteristic luminescence lifetime of gold nanorods is found to be less than 100 ps, which can be used to distinguish gold nanorods from other fluorescent labels and endogenous fluorophores in lifetime imaging.
|Item type:||Proceedings Paper|
|Keywords:||time, surface plasmon, contrast agents, cells, photoluminescence, optical-properties, nanoparticles, gold nanorods, metal-enhanced fluroescence, luminescence, microscopy, two-photon luminescence, fluorescence lifetime imaging, emission, biological imaging, Pharmacy and materia medica, Physics|
|Subjects:||Medicine > Pharmacy and materia medica|
Science > Physics
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
Faculty of Science > Physics
?? 120 ??
|Depositing user:||Pure Administrator|
|Date Deposited:||19 Oct 2012 12:59|
|Last modified:||12 Jun 2013 14:35|
Actions (login required)